Evidence map›Paper›PMID 42693195›Full record

ArticleScientific reports2026

Nicotiana glauca leaf extract exhibits synergistic antioxidant and anticancer activities revealed by phytochemical profiling and molecular docking.

Marwa M H Saeed, Sayed A Fayed, Rim Hamdy, Emad A Shalaby

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Marwa M H SaeedBiochemistry Department, Faculty of Agriculture, Cairo University, Giza, 12613, Egypt.
Sayed A FayedBiochemistry Department, Faculty of Agriculture, Cairo University, Giza, 12613, Egypt.
Rim HamdyBotany and Microbiology Department, Faculty of Science, Cairo University, Giza, 12613, Egypt.
Emad A ShalabyBiochemistry Department, Faculty of Agriculture, Cairo University, Giza, 12613, Egypt. emad.ahmed@agr.cu.edu.eg.ORCID 0000-0003-2900-4833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to characterize the phytochemical composition and antioxidant, cytotoxic and molecular docking profile of Nicotiana glauca Graham (Solanaceae), a wild plant species naturalized along the Wadi El Natrun-North Coast Road, Egypt. N. glauca was selected from a preliminary screening of ten co-occurring wild plant species collected during the summer of 2022 on the basis of its highest extraction yield (2.20%), the richest qualitative phytochemical profile among the ten species, and its strong antioxidant activity. The aqueous ethanolic leaf extract of N. glauca and its sixteen column fractions were subsequently evaluated using four chemical antioxidant assays: 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), potassium permanganate (KMnO₄), and dichlorophenolindophenol (DCPIP). Comprehensive phytochemical characterization was performed using thin-layer chromatography (TLC), TLC-bioautography, Fourier-transform infrared spectroscopy (FTIR), mass spectrometry,

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsNicotianaPhytochemicalsPlant ExtractsPlant LeavesCell Line, TumorHumansMolecular Docking SimulationAntineoplastic Agents, PhytogenicAntioxidantsPhytochemicalsPlant ExtractsAntioxidant activityCombination indexMolecular dockingNicotiana glaucaWild plants

Identifiers

PMID42693195
PMCPMC13542203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.