Evidence map›Paper›PMID 42690726›Full record

ArticleeLife2026

Complementary vertebrate

Kang-Han Lee, April M Stafford, Maria Pacheco-Vergara, Karol Cichewicz, Cesar P Canales, Nicolas Seban, Melissa Corea, Darlene Rahbarian, Kelly E Bonekamp, Grant R Gillie and 14 more

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors.

Kang-Han Lee *Department of Biology, Chungnam National University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-5369-1496
April M Stafford *Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, United States.
Maria Pacheco-VergaraDepartment of Molecular Pathology, New York University College of Dentistry, New York, United States.
Karol CichewiczDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, United States.ORCID https://orcid.org/0000-0001-5926-3663
Cesar P CanalesDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, United States.ORCID https://orcid.org/0000-0003-2505-8367
Nicolas SebanDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, United States.
Melissa CoreaDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, United States.
Darlene RahbarianDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, United States.
Kelly E BonekampDepartment of Physiology, Michigan State University, East Lansing, United States.
Grant R GillieDepartment of Physiology, Michigan State University, East Lansing, United States.
Dariangelly Pacheco-CruzDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, United States.ORCID https://orcid.org/0009-0009-8010-7513
Alyssa M GillDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, United States.
Hye-Eun HwangDepartment of Biology, Chungnam National University, Daejeon, Republic of Korea.
Yeong-Eun KimDepartment of Biology, Chungnam National University, Daejeon, Republic of Korea.ORCID https://orcid.org/0009-0001-0141-5131
Katie L UhlDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, United States.
Tara E JagerCorewell Health, Grand Rapids, United States.
Marwan ShinawiDivision of Genetics and Genomic Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, United States.
Xiaopeng LiDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, United States.
Andre ObenausDirector, Preclinical and Translational Imaging Center, School of Medicine, University of California Irvine, Irvine, United States.ORCID https://orcid.org/0000-0003-0081-6950
Shane R CrandallDepartment of Physiology, Michigan State University, East Lansing, United States.ORCID https://orcid.org/0000-0003-0611-3981
Juhee JeongDepartment of Molecular Pathology, New York University College of Dentistry, New York, United States.
Alex S NordDepartment of Psychiatry and Behavioral Sciences, University of California Davis, Davis, United States.ORCID https://orcid.org/0000-0003-4259-7514
Cheol-Hee KimDepartment of Biology, Chungnam National University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0002-3019-0699
Daniel VogtDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, United States.ORCID https://orcid.org/0000-0003-1876-5936

Funding

Integrative Pharmacological Sciences Training Program (IPSTP)T32GM142521 · NIGMS · MICHIGAN STATE UNIVERSITY · PI ANNE M. DORRANCE, Gina Marie Leinninger · 2021 to 2026
$2.4M
Causal biology of Chd8 haploinsufficiency in complex brain disordersR01MH120513 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI NORD, ALEXANDER · 2019 to 2023
$2.3M
Role of disrupted ASL pH regulation in small airways in CF lung disease pathogenesisR01HL153165 · NHLBI · MICHIGAN STATE UNIVERSITY · PI LI, XIAOPENG · 2021 to 2024
$2.2M
Genetic regulation of embryonic head mesenchyme patterningR01DE026798 · NIDCR · NEW YORK UNIVERSITY · PI JEONG, JUHEE · 2017 to 2021
$2.1M
Genetic regulation of embryonic head mesenchyme patterningR56DE026798 · NIDCR · NEW YORK UNIVERSITY · PI JEONG, JUHEE · 2024 to 2024
$366k
Cystic Fibrosis Foundation LI19XX0Korea National Institute of Health 2024-ER0519-00Korea National Institute of Health 2024-ER0703-00Korea National Institute of Health 2026-ER0602-00Korea National Institute of Health 2026-ER0807-00National Research Foundation of Korea RS-2024-00349650National Research Foundation of Korea RS-2024-00443043NHLBI NIH HHS R01 HL153165NIDCR NIH HHS R01 DE026798NIDCR NIH HHS R56 DE026798NIGMS NIH HHS T32 GM142521NIH HHS 5T32GM142521NIH HHS DE026798NIH HHS HL153165-01A1NIH HHS MH120513NIMH NIH HHS R01 MH120513
6 · The paper itself

Abstract

Monogenic syndromes are associated with neurodevelopmental changes that result in cognitive impairments and neurobehavioral phenotypes, including autism and seizures. Limited studies and resources are available to make meaningful headway into the underlying molecular mechanisms that result in these symptoms. One such example is DeSanto-Shinawi Syndrome (DESSH), a rare disorder caused by pathogenic variants in the

Indexed as

Intellectual DisabilityZebrafish ProteinsAnimalsBrainDisease Models, AnimalFemaleGABAergic NeuronsMaleMicePhenotypeZebrafishZebrafish ProteinsDESSHdevelopmental biologyGABAmouseneuroscienceWaczebrafish

Identifiers

PMID42690726
PMCPMC13541301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.