Evidence map›Paper›PMID 42690677›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2026

Association between physical activity bout length and physical functioning in older adults using absolute and relative intensity thresholds: a longitudinal cohort study.

Matti Hyvärinen, Antti Löppönen, Timo Aittokoski, Soren Brage, Tomas Gonzales, Taina Rantanen, Laura Karavirta

Abstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matti HyvärinenGerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0002-5086-3635
Antti LöppönenGerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0003-2232-6047
Timo AittokoskiGerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Soren BrageMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Tomas GonzalesMRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom.
Taina RantanenGerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0002-1604-1945
Laura KaravirtaGerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.ORCID 0000-0003-1372-2304

Funding

Academy of Finland 339391Academy of Finland 346462Academy of Finland 361968
6 · The paper itself

Abstract

backgroundDefining moderate-to-vigorous physical activity (MVPA) relative to individual capacity, instead of absolute intensity cut-points, may provide a more meaningful representation of physical activity in relation to age-related decline in physical functioning. We examined whether associations between MVPA energy expenditure (MVPAEE) and changes in physical functioning differ when MVPA is defined using absolute versus relative intensity cut-points, and whether bout length modifies these associations in older adults.

methodsThis 4-year follow-up study included 295 community-dwelling participants aged 75, 80, and 85 at baseline. Physical functioning was assessed using 6-min walking distance (6MWD) and five-times sit-to-stand test (FTSTS) time. MVPAEE was measured using thigh-worn accelerometers combined with chest-worn electrocardiography. MVPAEE accumulated in bouts of varying lengths was defined using both absolute intensity cut-points and cut-points relative to individual capacity. Associations between baseline MVPAEE and changes in physical functioning were examined using linear regression models and compositional data analysis.

resultsPhysical functioning declined during the follow-up. Higher relative MVPAEE was associated with a smaller decline in 6MWD (β = 0.27, 95% CI [0.08, 0.46]). Compositional data analyses showed that a higher proportion of MVPA relative to light-intensity activity energy expenditure was associated with a smaller decline in 6MWD (βilr = 0.25-0.31), independent of bout length. Absolute MVPAEE and bout-specific accumulation were not associated with changes in 6MWD or FTSTS.

conclusionsThe total volume and intensity of physical activity relative to an individual's capacity, rather than bout length, may be key factors in counteracting short-term declines in physical functioning in older adults.

Indexed as

AgingEnergy MetabolismExerciseAccelerometryAgedAged, 80 and overFemaleFollow-Up StudiesHumansLongitudinal StudiesMaleAccelerometerExercise intensityFunctional capacityPhysical activity energy expenditurePhysical fitness

Identifiers

PMID42690677
PMCPMC13626715

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.