Evidence map›Paper›PMID 42690572›Full record

ReviewGeroScience2026

Workplace stress and healthy aging: assessment strategies, research hypotheses, and pilot insights from the Semmelweis study.

Péter Varga, Virág Zábó, Andrea Lehoczki, Annamária Buda, Andrea Zsebe, Monika Fekete, Tamás Csípő, Vince Fazekas-Pongor, Ádám G Tabák, Stefano Tarantini and 5 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Péter Varga *Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Virág Zábó *Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Andrea Lehoczki *Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary. Andrea.M.Lehoczki@gmail.com.ORCID http://orcid.org/0000-0002-4285-7518
Annamária Buda *Institute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Andrea ZsebeAndrás Pető Faculty, Semmelweis University, Budapest, Hungary.
Monika FeketeInstitute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Tamás CsípőInstitute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Vince Fazekas-PongorInstitute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Ádám G TabákInstitute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Stefano TarantiniVascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Andriy YabluchanskiyVascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Róza ÁdányInstitute of Preventive Medicine and Public Health, Semmelweis University, Budapest, Hungary.
Béla MerkelyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
György PureblFodor Center for Prevention and Healthy Aging, Semmelweis University, Budapest, Hungary.
Zoltan UngvariVascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Workplace stress is an increasingly recognized determinant of both workforce well-being and healthy aging. However, few longitudinal studies have systematically integrated stress assessment into large occupational cohorts with an explicit focus on aging processes. The Semmelweis Study, launched in 2024, addresses this gap by embedding validated stress assessment tools into a comprehensive, multidisciplinary framework designed to explore the biological, psychological, and social determinants of healthy and unhealthy aging in a university workforce. This paper presents the conceptual foundation, methodology, and early applications of workplace stress assessment within the Semmelweis Study. We outline research hypotheses linking stress to aging outcomes and describe a pilot investigation among a high-risk subgroup-conductors trained at the András Pető Faculty of Semmelweis University. Stress is assessed using validated psychometric tools, including the Perceived Stress Scale, Effort-Reward Imbalance Questionnaire, Maslach Burnout Inventory, resilience measures, and social support scales. These are integrated with biological aging markers, cognitive assessments, mental health indicators, lifestyle factors, and detailed occupational data. A pilot study applying this framework was conducted among conductors, a professional group known for high emotional demands and role strain. Preliminary findings indicate elevated stress levels and burnout symptoms among conductors, with workload, perfectionism, and emotional burden identified as key stressors. Participants expressed strong interest in workplace-based stress management resources, informing plans for targeted interventions within this group. The integration of workplace stress assessment into the Semmelweis Study offers a novel platform for advancing healthy aging research and informing real-world prevention strategies. By systematically linking stress measurement to aging outcomes, and by addressing occupational stress through targeted interventions, Semmelweis University exemplifies how academic institutions can act as both research leaders and models of healthy workplace practices. These efforts align with the Semmelweis-EUniWell Workplace Health Promotion Model Program and contribute to broader European efforts to promote resilience, well-being, and healthy longevity across the working life course.

Indexed as

AgingBurnoutConductive educationEUniWellHealth promotionHealthy agingLongitudinal studyOccupational cohortOccupational healthResilienceSemmelweis studyStress assessmentUniversity workforceWorkplace stress

Identifiers

PMID42690572

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.