Evidence map›Paper›PMID 42690510›Full record

ArticleJapanese journal of ophthalmology2026

Epidemiology of macular dystrophy in Japan (2011-2020): a nationwide population-based study.

Hanako Ohashi Ikeda, Ai Otsuka, Takuro Kamei, Yuki Otsuka, Shogo Numa, Manabu Miyata, Akio Oishi, Shusuke Hiragi, Hiroaki Ueshima, Akitaka Tsujikawa and 2 more

Abstract read
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In one paragraph

Article in Japanese journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Hanako Ohashi IkedaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan. hanakoi@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0001-9572-8659
Ai OtsukaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Takuro KameiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Yuki OtsukaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Shogo NumaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Manabu MiyataDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Akio OishiDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Shusuke HiragiInstitute of Business and Accounting, Kansei Gakuin University, Osaka, Japan.
Hiroaki UeshimaCenter for Innovative Research and Education in Data Science, Institute for Liberal Arts and Sciences, Kyoto University, Kyoto, Japan.
Akitaka TsujikawaDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Masahiro MiyakeDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.
Hiroshi TamuraDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawahara, Sakyo, Kyoto, 606-8507, Japan.

Funding

Japan Society for the Promotion of Science JP 25K15322Japan Society for the Promotion of Science KAKENHI Grant Numbers JP 21K09740Ministry of Health, Labour and Welfare HealthMinistry of Health, Labour and Welfare Labour Sciences Research Grant (26FC1044)
6 · The paper itself

Abstract

purposeTo describe the characteristics and prevalence of macular dystrophy using a comprehensive national claims database in Japan. STUDY

designPopulation-based retrospective study using a nationwide claims database.

methodsApproximately 126 million individuals covered by Japan's universal health coverage system were included. Health insurance claims from 2011 to 2020 stored in the National Database of Health Insurance Claims (NDB) of Japan were analyzed. Patients with macular dystrophy, including best vitelliform macular dystrophy (BVMD), Stargardt disease (STGD), cone/cone-rod dystrophy, or central areolar choroidal dystrophy (CACD), were identified using diagnostic codes recorded in the database. The population-based prevalence of diagnosed macular dystrophy was calculated, and age-standardized rates were derived using the WHO standard world population.

resultsBetween 2011 and 2020, 1,268 patients with BVMD, 460 with STGD, 5758 with cone/cone-rod dystrophy, and 280 with CACD were identified in the NDB. As of October 1, 2020, the corresponding prevalence rates were 10.05, 3.65, 45.65, and 2.35 per 1,000,000 persons, respectively.

conclusionThis nationwide study provides updated epidemiological estimates of macular dystrophy in Japan. These findings may inform clinical management, healthcare planning, and future research on macular dystrophy.

Indexed as

Macular dystrophyPrevalence

Identifiers

PMID42690510

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