Evidence map›Paper›PMID 42690270›Full record

ArticleWorld journal of urology2026

Global burden and inequality of childhood kidney cancer (1990-2050): a systematic analysis for the global burden of disease study 2021.

Yanheng Sun, Qian Xu, Xin Dai, Song Li, Jiahui Chu, Mingchi Ma, Pei Wang, Lian Liu

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Article in World journal of urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yanheng Sun *Department of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Qian Xu *Department of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Xin Dai *Department of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Song LiDepartment of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Jiahui ChuDepartment of Pharmacy, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Mingchi MaDepartment of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Pei WangDepartment of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China.
Lian LiuDepartment of Medical Oncology, Cheeloo College of Medicine, Qilu Hospital, Shandong University, Jinan, 250012, Shandong, China. lianliu@sdu.edu.cn.ORCID https://orcid.org/0000-0001-5868-4482

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChildhood kidney cancer is one of the most common pediatric malignancies without comprehensive assessments of its global burden. We aimed to quantify the global burden from 1990 to 2021 and project trends to 2050.

methodsData on incidence, mortality, and disability-adjusted life years (DALYs) for childhood kidney cancer were obtained from the Global Burden of Disease (GBD) 2021. Temporal trends were analyzed using Joinpoint regression. Spearman's rank correlation was used to evaluate the association between disease burden and the sociodemographic index (SDI). Future burden trends were predicted with a Bayesian age-period-cohort (BAPC) model.

resultsIn 2021, there were 9576 global incident cases of childhood kidney cancer, resulting in 3,063 deaths and 268,049 DALYs. From 1990 to 2021, global burden of childhood kidney cancer declined overall. However, substantial disparities persisted across regions and SDI levels. Low-SDI regions experienced disproportionately poorer prognosis, while children under five years and boys bore the greatest burden. Projections indicate continued declines in global burden through 2050.

conclusionDespite overall declines in the global burden of childhood kidney cancer, substantial disparities persist across sociodemographic contexts. These findings emphasize the importance of improving early diagnosis, access to standardized treatment, and delivery of pediatric oncology care in high-burden settings.

Indexed as

Global Burden of DiseaseKidney NeoplasmsAdolescentChildChild, PreschoolDisability-Adjusted Life YearsFemaleGlobal HealthHumansIncidenceInfantMaleQuality-Adjusted Life YearsChildhood kidney cancerDisability-adjusted life yearsGlobal burden of diseaseIncidenceMortalitySocio-demographic index

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PMID42690270

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.