Evidence map›Paper›PMID 42690267›Full record

ReviewInternational urogynecology journal2026

Music as a Nonpharmacological Adjunct for Reducing Pain, Anxiety, and Physiological Stress During Cystoscopy: A Systematic Review and Meta-Analysis.

Mohamed Abo Zeid, Michael Gerges, Kareem Khalefa, Amira A Aboali, Ahmed Talkhan, Lamees Taman, Amr M Abou Elezz

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In one paragraph

Review in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed Abo ZeidFaculty of Medicine, Tanta University, Tanta, Egypt.ORCID http://orcid.org/0009-0007-8165-9470
Michael GergesFaculty of Medicine, Tanta University, Tanta, Egypt.
Kareem KhalefaFaculty of Medicine, Tanta University, Tanta, Egypt.
Amira A AboaliDepartment of Diagnostic and Interventional Radiology, Damanhour Teaching Hospital, General Organization for Teaching Hospitals and Institutes, Damanhour, Egypt.ORCID http://orcid.org/0000-0002-8547-4672
Ahmed TalkhanFaculty of Medicine, Mansoura University, Mansoura, Egypt.ORCID http://orcid.org/0009-0009-7975-6479
Lamees TamanFaculty of Medicine, Tanta University, Tanta, Egypt.
Amr M Abou ElezzFaculty of Medicine, Tanta University, Tanta, Egypt. Amr_31060929@med.tanta.edu.eg.ORCID http://orcid.org/0009-0004-8806-2624

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisCystoscopy is a commonly performed invasive urological procedure often associated with pain and anxiety, negatively affecting patient compliance and satisfaction. Music has been proposed as a simple, low-cost, nonpharmacological intervention to reduce procedural discomfort and stress. This systematic review and meta-analysis evaluated the effectiveness of music during cystoscopy.

methodsFollowing Preferred Reporting Items for Systematic Reviews and Meta-Analyses and Cochrane guidelines, PubMed, Scopus, Web of Science, and the Cochrane Library were searched through 5 January 2026. Randomized controlled trials (RCTs) including male patients undergoing cystoscopy and comparing music with a placebo were eligible. Primary outcomes were changes in pain and anxiety scores; secondary outcomes were heart rate and systolic blood pressure. Data were pooled using a random-effects model, and study quality was assessed using the Cochrane Risk-of-Bias 2 tool.

resultsThirteen RCTs comprising 1,347 participants were included. Music significantly reduced pain (MD = -1.39, 95% CI -1.87 to -0.91), anxiety (MD = -7.35, 95% CI -12.16 to -2.56), and heart rate (MD = -3.31, 95% CI -4.47 to -2.15) compared with control. No significant reduction was observed in systolic blood pressure (MD = -1.27, 95% CI -4.08 to 1.53). Subgroup analysis showed consistent reductions in pain and heart rate for both rigid and flexible cystoscopy. Anxiety reduction was significant in flexible cystoscopy but not in rigid procedures.

conclusionMusic is a safe, inexpensive adjunct that effectively reduces pain, anxiety, and heart rate during cystoscopy and may enhance patient comfort and procedural tolerance.

Indexed as

AnxietyCystoscopyMusicPain

Identifiers

PMID42690267

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.