Evidence map›Paper›PMID 42689918›Full record

ArticleJACC. Case reports2026

VA-ECMO Weaning in Low-Flow Low-Gradient Aortic Stenosis Post STEMI and ECPR.

Erich Burton, David Sosa, Michael Williams, Erik Kraai, Trenton Wray, Nicole Collantes-Silva, Rudra Pratap Singh, Pamela Hsu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Erich BurtonDepartment of Emergency Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA; Center for Adult Critical Care, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA. Electronic address: Erburton@salud.unm.edu.
David SosaDepartment of Internal Medicine, Interventional Cardiology, University of New Mexico, Albuquerque, New Mexico, USA.
Michael WilliamsDepartment of Internal Medicine, Pulmonary and Critical Care, University of New Mexico, Albuquerque, New Mexico, USA.
Erik KraaiCenter for Adult Critical Care, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA; Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Trenton WrayDepartment of Emergency Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA; Center for Adult Critical Care, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
Nicole Collantes-SilvaDepartment of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Rudra Pratap SinghDepartment of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA.
Pamela HsuDepartment of Internal Medicine, Cardiology, University of New Mexico, Albuquerque, New Mexico, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLow-flow, low-gradient (LF-LG) severe aortic stenosis (AS) in post-ST-elevation myocardial infarction cardiogenic shock supported with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) presents complex diagnostic and therapeutic challenges. Retrograde extracorporeal membrane oxygenation flow alters cardiac loading conditions and transvalvular flow, complicating accurate assessment of valvular disease. CASE SUMMARY: A 52-year-old woman with inferolateral ST-elevation myocardial infarction complicated by ventricular fibrillation cardiac arrest, was placed on VA-ECMO support. Extracorporeal membrane oxygenation weaning attempts failed due to severe bicuspid LF-LG AS. After multidisciplinary evaluation, she underwent transcatheter aortic valve implantation and was subsequently successfully weaned from VA-ECMO. DISCUSSION: Mechanical circulatory support alters preload, afterload, and transvalvular flow, making differentiation between true severe AS and low-flow states from cardiogenic shock or ventricular dysfunction difficult. No societal guidelines exist for grading LF-LG AS severity or guiding VA-ECMO weaning in this setting. TAKE-HOME MESSAGES: VA-ECMO complicates LF-LG AS assessment. Multimodal, multidisciplinary evaluation enables accurate diagnosis and appropriate intervention.

Indexed as

cardiogenic shockextracorporeal membrane oxygenationmechanical circulatory supportmyocardial infarctiontranscatheter aortic valve implantationvalvular heart diseasevalvular stenosis

Identifiers

PMID42689918
PMCPMC13554880

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.