Trial reportGut microbes2026
Gut microbiota and metabolic alterations in participants with flatulence identify
Ruimin Chen, Chuan Zhang, Shikai Yan, Chengcheng Zhang, Yilin Ren, Gang Wang, Shumao Cui, Wenwei Lu, Bo Yang, Xiaomei Lyu and 5 more
Abstract readRandomized Controlled Trial
In one paragraphTrial report in Gut microbes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
15 authors.
Ruimin ChenState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Chuan ZhangState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Shikai YanState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Chengcheng ZhangState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Yilin RenDepartment of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China.
Gang WangState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0003-2007-2143 Shumao CuiState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-7055-0484 Wenwei LuState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-8636-9815 Bo YangState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Xiaomei LyuState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Peijun TianState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-7833-1745 Jianxin ZhaoState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Fengwei TianState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-8511-4546 Yuzheng XueDepartment of Gastroenterology, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu Province, People's Republic of China.ORCID 0000-0003-1020-7059 Qixiao ZhaiState Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu, People's Republic of China.ORCID 0000-0002-0605-2675 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Flatulence is closely associated with gut dysbiosis, yet the characteristic microbial signatures, metabolic alterations, and actionable intervention targets remain unclear. This limited mechanistic understanding has hindered the development of precise microbiota-based strategies for managing flatulence. Here, we found that participants with flatulence exhibited marked shifts in gut microbial functions and fecal metabolic profiles compared with healthy controls, characterized by enhanced abnormal fermentation, enrichment of oxidative stress-related functions, elevated low-grade inflammatory signatures, and reduced anti-inflammatory and mucosal-protective metabolic features.
Indexed as
DysbiosisFaecalibacterium prausnitziiGastrointestinal MicrobiomeProbioticsAdultBacteriaBifidobacterium longumButyratesDouble-Blind MethodFecesFemaleFermentationHumansMaleButyratesclinical trialFlatulencegasgut microbiotaprobiotics
Identifiers
PMID42689867
PMCPMC13556954
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