Evidence map›Paper›PMID 42689380›Full record

ArticleChemistry & biodiversity2026

Synthesis, Characterization, and Multifunctional Bioactivity of ZnO/CuO@Amoxicillin Nanocomposites: A Synergistic Nano-Platform With Potent Antioxidant, Anti-Inflammatory, Antidiabetic, and Anti-Cholinesterase Activities.

Hocine Sadam Nesrat, Abdelatif Aouadi, Ibtissam Laib, Salah Eddine Laouini, Abderrhmane Bouafia, Djamila Hamada Saoud, Halima Zidane, Hafidha Terea, Mahmood M S Abdullah, Tomasz Trzepieciński and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hocine Sadam NesratLaboratory of Analysis, Treatment and Recovery of Environmental Pollutants and Products, Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.
Abdelatif AouadiLaboratory of Biotechnology Biomaterials and Condensed Matter (LBBCM), Faculty of Technology, University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0009-0003-3300-2109
Ibtissam LaibFaculty of Biology, Department of Cellular and Molecular Biology, University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0002-9521-3003
Salah Eddine LaouiniLaboratory of Biotechnology Biomaterials and Condensed Matter (LBBCM), Faculty of Technology, University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0002-6609-4623
Abderrhmane BouafiaLaboratory of Biotechnology Biomaterials and Condensed Matter (LBBCM), Faculty of Technology, University of El Oued, El Oued, Algeria.ORCID https://orcid.org/0000-0001-5266-7796
Djamila Hamada SaoudProcess Engineering Laboratory, Applied Sciences Faculty, Kasdi Merbah University, Ouargla, Algeria.ORCID https://orcid.org/0000-0002-9681-7810
Halima ZidaneLaboratory Valorization and Technology of Saharan Resources (VTRS), University of El Oued, El Oued, Algeria.
Hafidha TereaDepartment of Process Engineering and Petrochemistry, Faculty of Technology, University of El Oued, El Oued, Algeria.
Mahmood M S AbdullahDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-8057-8376
Tomasz TrzepiecińskiDepartment of Manufacturing Processes and Production Engineering, Rzeszów University of Technology, Rzeszów, Poland.ORCID https://orcid.org/0000-0002-4366-0135
Dalila Saidane-MosbahiLaboratory of Analysis, Treatment and Recovery of Environmental Pollutants and Products, Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.

Funding

Algerian Directorate General for Scientific Research and Technological Development-DGRSDT and El-Oued University
6 · The paper itself

Abstract

A ZnO/CuO@amoxicillin nanocomposite was synthesized via a sol-gel route and characterized as a biphasic wurtzite ZnO-monoclinic CuO system with crystallite sizes of about 10-12 nm and an optical band gap of 3.30-3.36 eV, indicating defect-rich interfaces favorable for redox activity. In antidiabetic assays, the nanocomposite showed strong inhibitory effects on alpha-amylase (IC

Indexed as

Anti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsCholinesterase InhibitorsCopperHypoglycemic AgentsNanocompositesZinc OxideAcetylcholinesterasealpha-Amylasesalpha-GlucosidasesAnimalsHumansAcetylcholinesterasealpha-Amylasesalpha-GlucosidasesAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsCholinesterase InhibitorsCoppercupric oxideHypoglycemic AgentsZinc Oxideamoxicillin functionalizationantidiabeticanti‐inflammatoryantioxidant activityneuroprotectiveZnO/CuO nanocomposite

Identifiers

PMID42689380
PMCPMC13539476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.