Evidence map›Paper›PMID 42689321›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2026

Targeting Thrombopoietin/MPL Signaling to Mitigate JAK2V617F-Driven Cardiac Microvascular Disease.

Xiaoxi Yang, Kyla Masarik, Xiaochuan Sun, Fangfang Zhang, Kirsten Zheng, Haoyi Zheng, Huichun Zhan

Abstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Xiaoxi YangDepartment of Medicine, Stony Brook School of Medicine, NY (X.Y., K.M., X.S., F.Z., H. Zhan).
Kyla MasarikDepartment of Medicine, Stony Brook School of Medicine, NY (X.Y., K.M., X.S., F.Z., H. Zhan).
Xiaochuan SunDepartment of Medicine, Stony Brook School of Medicine, NY (X.Y., K.M., X.S., F.Z., H. Zhan).
Fangfang ZhangDepartment of Medicine, Stony Brook School of Medicine, NY (X.Y., K.M., X.S., F.Z., H. Zhan).ORCID 0000-0002-6094-4340
Kirsten ZhengHarborfields High School, Greenlawn, NY (K.Z.).
Haoyi ZhengCardiac Imaging, The Heart Center, Saint Francis Hospital, Roslyn, NY (H. Zheng).ORCID 0000-0003-2770-2515
Huichun ZhanDepartment of Medicine, Stony Brook School of Medicine, NY (X.Y., K.M., X.S., F.Z., H. Zhan).ORCID 0000-0002-0359-0371

Funding

Cell Competition in Myeloproliferative NeoplasmsR01CA266294 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI Huichun Zhan · 2022 to 2026
$1.8M
BLRD VA I01 BX003947BLRD VA I01 BX005584NCI NIH HHS R01 CA266294
6 · The paper itself

Abstract

backgroundIndividuals with

methodsWe generated chimeric mice with

resultsMice with

conclusions

Indexed as

endocardiumhematopoiesismicrocirculationreceptorsthrombopoietin

Identifiers

PMID42689321
PMCPMC13595420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.