ArticleBioinformatics advances2026
TimeTraits: extracting functional traits from biological time-series in R.
Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motivation: It is currently challenging for scientists to extract meaningful parameters from circadian rhythms that dynamically change over time (i.e. non-stationary rhythms). Circadian rhythms may be non-stationary due to dynamic conditions, such as changes in photoperiod. Circadian rhythms are also nonstationary when plants are suddenly placed under continuous light conditions after a period of entrainment, as their clocks slowly drift without external entrainment signals. Results: TimeTraits provides a series of functions to enable the extraction of parameters from time series data using Functional Data Analysis methods. We demonstrate its utility in dissecting the changes in curve shape of a circadian clock bioluminescence marker, following a photoperiod shift in wildtype and phyB Arabidopsis. Availability and implementation: TimeTraits is available in CRAN: https://cran.r-project.org/web/packages/TimeTraits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.