Evidence map›Paper›PMID 42689157›Full record

ArticleMedComm2026

Unveiling Functional Architecture of Human Thalamus: AStereoelectroencephalography Study.

Liankun Ren, Di Wu, Cuiping Xu, Lei Qi, Guangyuan Jin, Xueyuan Wang, Yueyang Cheng, Jialin Du, Siyi Wang, Dongmei Hu and 15 more

Abstract read
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Liankun RenDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0001-5147-3068
Di WuDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0002-8491-3477
Cuiping XuNational Center for Neurological Disorders Beijing China.
Lei QiDepartment of Neurology China Rehabilitation Research Center Beijing China.ORCID https://orcid.org/0000-0003-3300-5345
Guangyuan JinDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0002-7334-802X
Xueyuan WangNational Center for Neurological Disorders Beijing China.ORCID https://orcid.org/0000-0003-2463-748X
Yueyang ChengDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0009-0001-6212-3714
Jialin DuDepartment of Pharmacy Phase I Clinical Trial Center Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0001-8151-9311
Siyi WangDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.
Dongmei HuDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.
Junliang GeDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.
Yixi ZhengDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.
Yihe WangDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.
Huaqiang ZhangDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0002-1780-158X
Yang DaiDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.
Hao YanDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.
Runshi GaoDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0003-4375-6046
Ying GaoDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.
Zeyu ZhangDepartment of Science The University of Melbourne Victoria Australia.
Penghu WeiDepartment of Neurosurgery Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0002-4529-7691
Yuping WangDepartment of Neurology Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0002-6482-9710
Philippe KahaneGrenoble Alpes University Hospital Center Grenoble Alpes University, Inserm, U1216 Grenoble Institute of Neurosciences Grenoble France.ORCID https://orcid.org/0000-0002-5655-2571
Fabrice BartolomeiInstitut de Neurosciences des Systèmes Inserm, INS Aix-Marseille University Marseille France.ORCID https://orcid.org/0000-0002-1678-0297
Tao YuNational Center for Neurological Disorders Beijing China.ORCID https://orcid.org/0000-0001-6885-7105
Guoguang ZhaoClinical Research Center of Epilepsy Xuanwu Hospital Capital Medical University Beijing China.ORCID https://orcid.org/0000-0002-7569-5252

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a critical hub in the thalamo-cortical circuit, the human thalamus engages in a spectrum of fundamental and advanced brain functions through widely distributed circuits. Clinically, dysfunction of thalamo-cortical circuits is shown to be profoundly implicated in a wide range of neurological and psychiatric diseases. Nevertheless, the neuroanatomical substrates governing these functions of the thalamus have rarely been directly mapped in humans. Here, we overviewed the acute responses of direct electrical stimulation (DES) delivered to the distributed thalamus sites in 52 epilepsy patients admitted for presurgical stereoelectroencephalography. Specifically, DES of the thalamus evoked a broad spectrum of in-situ responses spanning fundamental functions such as sensory and motor processing, extending to complex neural operations encompassing neurovegetative regulation, cognitive processing, emotional modulation, and multimodal responsiveness. Moreover, through the integration of DES with functional human connectome (

Indexed as

direct electrical stimulationepilepsyfunctional connectivitythalamus

Identifiers

PMID42689157
PMCPMC13537012

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.