Evidence map›Paper›PMID 42689137›Full record

ArticleJournal of dental sciences2026

Histologic and histomorphometric assessments of provisionally restored dental implants.

Myron Nevins, Stefano Parma-Benfenati, Primo Galletti, Lucrezia Parma-Benfenati, Paolo Nava, Miruna Maracine, Traian Comanescu, Chia-Yu Jennifer Chen, David M Kim

Abstract read
In one paragraph

Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Myron NevinsDepartment of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, USA.
Stefano Parma-BenfenatiDepartment of Surgical Science, Section of Periodontology, University of Turin, Turin, Italy.
Primo GallettiDepartment of Translational Medicine, School of Dentistry, University of Ferrara, Ferrara, Italy.
Lucrezia Parma-BenfenatiDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
Paolo NavaDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
Miruna MaracinePrivate Practice (Dentalevo Clinic), Bucharest, Romania.
Traian ComanescuPrivate Practice (ARRA Dental Clinique), Bucharest, Romania.
Chia-Yu Jennifer ChenDepartment of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, USA.
David M KimDepartment of Oral Medicine, Infection and Immunity, Division of Periodontology, Harvard School of Dental Medicine, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Immediate provisionalization of dental implants has been considered a safe and predictable treatment modality; however, histologic evidence from human biopsies remains limited. The aim of this study was to evaluate bone-to-implant contact (BIC) and clinical outcomes of immediately provisionalized implants. Materials and methods: This prospective clinical study included 5 patients receiving 7 immediately provisionalized implants in both the maxilla and mandible. All implants achieved primary stability and were restored with provisional restorations that were loaded with light centric contacts. Biopsies were obtained at 3 months and processed for histologic and histomorphometric analysis. Results: All implants remained clinically stable throughout the observation period, resulting in a 100 % survival rate. Histologic examination confirmed direct bone-to-implant contact (BIC), with newly formed lamellar bone observed along the implant surface. Histomorphometric analysis revealed a mean BIC of 76.51 ± 7.91 %, which is comparable to values reported in conventionally loaded implants. No adverse biological or prosthetic events were observed. Conclusion: Immediate provisional implants demonstrated substantial BIC and favorable clinical outcomes in this study. These findings provide histologic confirmation that immediate provisionalization is a safe and efficacious protocol when primary stability and careful occlusal management are achieved.

Indexed as

Dental implantsDental restorationHistologyHumansOsseointegrationTemporary

Identifiers

PMID42689137
PMCPMC13536414

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.