ArticleCureus2026
Celiac Disease Spectrum Among Patients With Iron Deficiency Anemia: A Retrospective Study From a Tertiary Care Center in Morocco.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Celiac disease is a chronic immune-mediated enteropathy triggered by gluten in genetically susceptible individuals. Its presentation is variable and may range from classic malabsorptive symptoms to atypical or extraintestinal manifestations. Iron deficiency anemia (IDA) is a common extraintestinal presentation and may occur without gastrointestinal symptoms, which can delay diagnosis. Objective To determine the hospital-based proportion of celiac disease among patients with iron deficiency anemia at Cheikh Khalifa International University Hospital, Casablanca, Morocco, and to describe their clinical, biological, serological, and histological characteristics. Methods We conducted a retrospective, descriptive, single-center study of patients with IDA followed in the Department of Medical Hematology between January 2020 and September 2025. Among 635 patients with IDA, 97 underwent anti-tissue transglutaminase IgA (anti-tTG IgA) testing, and 40 underwent duodenal biopsy based on clinical suspicion. Celiac disease was confirmed by positive anti-tTG IgA serology and compatible duodenal histology. One patient with strongly positive serology and normal histology was classified as having potential celiac disease according to the Oslo definitions. Data were collected retrospectively from medical records and hospital databases. Results Among the 635 patients with IDA, 97 underwent serological testing, of whom 18 were positive, while 40 underwent duodenal biopsy. Seventeen patients had biopsy-confirmed celiac disease, and one additional patient was classified as having potential celiac disease, resulting in an 18-patient celiac disease spectrum cohort and a crude hospital-based proportion of 2.83%. This figure reflects selective, clinically driven testing and should not be extrapolated to the general population or to unselected patients with IDA. All 18 patients were female, with a mean age of 29.9 years. Asthenia was reported in all patients, and intestinal discomfort was the most frequent digestive symptom (83.3%). Weight loss, chronic diarrhea, and steatorrhea were reported in 66.6%, 44.4%, and 27.7% of patients, respectively. Extra-intestinal manifestations included arthralgia (38.9%), bone pain (27.7%), oral aphthous ulcers (11.1%), amenorrhea (22.2%), and recurrent miscarriage (16.7%). Mean hemoglobin was 9.9 ± 1.4 g/dL, and 94.4% of patients had ferritin levels below 15 ng/mL. Among the nine patients assessed for micronutrient status, folate and vitamin D deficiencies were found in 44.4% and 66.7%, respectively. Anti-tTG IgA was positive in all 18 patients, and Marsh III lesions were found in 66.6% of cases. Gastritis and
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.