Evidence map›Paper›PMID 42689115›Full record

ReviewFrontiers in oncology2026

The Cancer Epitope Database and Analysis Resource (CEDAR): current capabilities and future directions.

Zeynep Koşaloğlu-Yalçın, Ibel Carri, Daniel Marrama, Eve Richardson, Jason Greenbaum, Nina Blazseka, Randi Vita, Hannah Carter, Morten Nielsen, Bjoern Peters and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zeynep Koşaloğlu-YalçınCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Ibel CarriCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Daniel MarramaCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Eve RichardsonCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Jason GreenbaumBioinformatics Core, La Jolla Institute for Immunology, La Jolla, San Diego, CA, United States.
Nina BlazsekaCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Randi VitaCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Hannah CarterDepartment of Medicine, University of California, San Diego, La Jolla, CA, United States.
Morten NielsenDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Bjoern PetersCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.
Alessandro SetteCenter for Vaccine Innovation, La Jolla Institute for Immunology, La Jolla, CA, United States.

Funding

THE CANCER EPITOPE DATABASE AND ANALYSIS RESOURCEU24CA248138 · NCI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI PETERS, BJOERN, SETTE, ALESSANDRO · 2021 to 2025
$4.6M
NCI NIH HHS U24 CA248138
6 · The paper itself

Abstract

Cancer epitopes, the molecular structures recognized by T and B cells at the tumor interface, are central to understanding antitumor immunity and developing immunotherapies. Yet despite the rapid growth of cancer immunology data, a comprehensive, continuously updated, and accessible resource for cancer epitope data has been lacking. The Cancer Epitope Database and Analysis Resource (CEDAR, cedar.iedb.org) was established in 2021 to fill this gap, providing curated experimental epitope data alongside a suite of cancer-specific computational tools for epitope prediction and analysis. Built on the validated infrastructure of the Immune Epitope Database (IEDB), CEDAR integrates cancer epitope data with biological, immunological, and clinical context, enabling researchers to explore immune recognition of tumors, identify candidate targets for immunotherapy, and benchmark prediction methods. Here we describe CEDAR's current capabilities, report on progress in curation, database development, and tool availability, and outline the opportunities and challenges ahead for expanding its scope and utility to the cancer research community.

Indexed as

bioinformatics & computational biologycancer epitopescancer immunology and immunotherapydatabaseepitope prediction

Identifiers

PMID42689115
PMCPMC13536732

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.