ArticleJournal of dental sciences2026
Composite regenerative matrix for barrier-free bone regeneration: Full-mouth rehabilitation with long-term stability.
Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
We described a novel composite regenerative matrix (CRM) designed to improve the handling and stability of sticky bone and advanced platelet-rich fibrin (PRF). The CRM combined autologous fibrinogen glue, allograft, and type I collagen and was processed through repeated compression cycles to enhance graft cohesion. A patient with generalized advanced periodontitis presented with severe vertical and horizontal alveolar bone loss, including a rare no-wall defect in the anterior mandible was reported in this study. Following periodontal therapy and extraction of unrestorable teeth, the CRM was used for socket regeneration and ridge augmentation without a membrane. Delayed implant placement and full-arch rehabilitation were subsequently performed. Clinical and radiographic outcomes demonstrated substantial vertical bone gain, stable peri-implant tissues, and favorable esthetics. The 6 -year postoperative cone-beam computed tomography confirmed cortical bone formation. Thus, the CRM may provide a clinically feasible and predictable membrane-free option for complex alveolar defects for which conventional guided bone regeneration is limited.
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