Evidence map›Paper›PMID 42689064›Full record

ArticleJournal of dental sciences2026

Pathogenic oral microbiota abundance is associated with reduced bite force in patients with periodontitis.

Chih-Chieh Wen, Thu Ya Linn, Ting-Yi Renn, Hui Yin Nam, Chia-Chen Hsu, Yi-Jen Lin, Yi-Fan Wu, Wei-Jen Chang

Abstract read
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Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chih-Chieh WenGraduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Thu Ya LinnSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Ting-Yi RennSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Hui Yin NamDepartment of Pre-clinical Sciences, M. Kandiah Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Kajang, Selangor, Malaysia.
Chia-Chen HsuSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Yi-Jen LinDepartment of Biomedical Engineering, School of Health and Medical Engineering, Ming Chuan University, Taoyuan, Taiwan.
Yi-Fan WuDepartment of Biomedical Engineering, School of Health and Medical Engineering, Ming Chuan University, Taoyuan, Taiwan.
Wei-Jen ChangSchool of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background /purpose: Periodontitis leads to tissue destruction and functional impairment, but the interplay between microbiota, clinical parameters, and biomechanics remains unclear. This study aimed to quantitatively correlate specific oral microbial signatures and clinical inflammatory indicators with bite force in patients with periodontitis. Materials and methods: Fifteen patients with stage III-IV periodontitis and 15 periodontally healthy controls were recruited. Clinical parameters (Probing Depth, Clinical Attachment Loss, Bleeding on Probing, Plaque Index) and MBF (pressure-sensitive film) were recorded. Supragingival plaque was analyzed through 16S rRNA gene sequencing (PacBio SMRT) to determine microbial composition. Correlation analyses were performed. Results: The periodontitis group had significantly higher CAL (4.97 ± 1.18 vs. 2.49 ± 0.21 mm) and BOP (49.16 ± 17.97% vs. 14.52 ± 5.29%), and significantly lower MBF (561.17 vs. 891.46 N) (all Conclusion: Bite force decline in periodontitis is directly associated with both clinical inflammation (BOP) and specific pathogenic bacterial loads (e.g.,

Indexed as

Bite forceDental plaqueFull-length 16S rRNA sequencingOral microbiotaPeriodontitis

Identifiers

PMID42689064
PMCPMC13536395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.