Evidence map›Paper›PMID 42689059›Full record

ArticleJournal of dental sciences2026

Association of

Pei-Hsuan Lu, Chih-Huang Tseng, Yi-Ping Wang, Jang-Jaer Lee, Shih-Jung Cheng, Catherine Huang, Hao-Hueng Chang, Julia Yu-Fong Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pei-Hsuan LuDepartment of Dentistry, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan.
Chih-Huang TsengGraduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.
Yi-Ping WangGraduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.
Jang-Jaer LeeDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Shih-Jung ChengDepartment of Dentistry, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
Catherine HuangStanford University, Stanford, CA, USA.
Hao-Hueng ChangGraduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.
Julia Yu-Fong ChangGraduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Mutations in mitogen-activated protein kinase (MAPK) and sonic hedgehog (SHH) pathways are the most common genetic changes reported in ameloblastomas. This study tried to find the mutational landscape of ameloblastomas in Taiwan and clarify the role of SHH pathway in the pathogenesis of ameloblastoma. Materials and methods: Sanger sequencing of the mutation hot spots in Results: Conclusion: The concomitant activation of both the MAPK and SHH pathways is frequently found in ameloblastomas. GLI1 may stimulate the keratin production through a paracrine regulatory mechanism. SHH pathway is most likely a later event in the pathogenesis of ameloblastomas.

Indexed as

AmeloblastomaBRAF V600E mutationCK17GLI1MAPK pathwaySHH pathway

Identifiers

PMID42689059
PMCPMC13536368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.