Evidence map›Paper›PMID 42688974›Full record

ArticleOxford medical case reports2026

Multisystem FDG-avid sarcoidosis with osseous involvement mimicking disseminated metastatic malignancy.

Jamil Wafi, Mohammed Alkhanafsa, Soud Deek, Aya Alqattaa, Mohammed Alkhatib, Bara Wazwaz, Irfan Ul Haq

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jamil WafiInternal Medicine Department, Hamad General Hospital, Hamad Medical Corporation, Al Rayyan Road, Doha, P.O. Box 3050, Qatar.ORCID https://orcid.org/0009-0006-7531-0232
Mohammed AlkhanafsaInternal Medicine Department, Hamad General Hospital, Hamad Medical Corporation, Al Rayyan Road, Doha, P.O. Box 3050, Qatar.ORCID https://orcid.org/0009-0002-4983-2855
Soud DeekInternal Medicine Department, Hamad General Hospital, Hamad Medical Corporation, Al Rayyan Road, Doha, P.O. Box 3050, Qatar.
Aya AlqattaaInternal Medicine Department, Islamic University of Gaza, Al-Thalathini Street, Al-Rimal, Gaza City, P.O. Box 108, Palestine.
Mohammed AlkhatibPulmonary Department, Hamad General Hospital, Hamad Medical Corporation, Al Rayyan Road, Zone 37, Doha, P.O. Box 3050, Qatar.
Bara WazwazPathology Department, Hamad General Hospital, Hamad Medical Corporation, Al Rayyan Road, Zone 37, Doha, P.O. Box 3050, Qatar.
Irfan Ul HaqPulmonary Department, Hamad General Hospital, Hamad Medical Corporation, Al Rayyan Road, Zone 37, Doha, P.O. Box 3050, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis may closely mimic disseminated malignancy on FDG-PET/CT because active granulomatous inflammation can demonstrate intense multisystem FDG uptake. We report a 59-year-old woman with previously diagnosed pulmonary sarcoidosis who presented with acute dyspnea and right leg pain and was found to have segmental and subsegmental pulmonary emboli on CT pulmonary angiography. FDG-PET/CT demonstrated extensive intensely hypermetabolic mediastinal, hilar, abdominal and pelvic lymphadenopathy with pulmonary, hepatic, splenic and multifocal osseous involvement, including a right iliac lesion (SUVmax 12.3), raising strong suspicion for disseminated metastatic malignancy or lymphoproliferative disease. CT-guided biopsy of the iliac lesion revealed non-necrotizing granulomatous inflammation without evidence of malignancy or infection, confirming multisystem sarcoidosis with osseous involvement. This case highlights the importance of histological confirmation when FDG-PET/CT findings in sarcoidosis mimic metastatic disease.

Indexed as

FDG-PETmultisystem diseaseosseous sarcoidosispulmonary embolismsarcoidosis

Identifiers

PMID42688974
PMCPMC13537522

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.