Evidence map›Paper›PMID 42688796›Full record

ReviewInternational journal of dentistry2026

Clinical and Pathophysiological Significance of Trace Elements in Oral Potentially Malignant Disorders and Oral Cancer: A 20-Year Narrative Review for Evidence-Based Public Health Intervention.

Hannah Haneef, Ravikiran Ongole, Joanna Baptist, Sara J Ommen, Prasanna Mithra

Abstract readReview
In one paragraph

Review in International journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hannah HaneefOral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India, manipal.edu.
Ravikiran OngoleOral Medicine and Radiology, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India, manipal.edu.ORCID https://orcid.org/0000-0001-7075-2708
Joanna BaptistOral and Maxillofacial Surgery, Manipal College of Dental Sciences Mangalore, Manipal Academy of Higher Education, Manipal, India, manipal.edu.ORCID https://orcid.org/0000-0003-1075-8950
Sara J OmmenCommunity Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India, manipal.edu.ORCID https://orcid.org/0009-0006-0732-3058
Prasanna MithraCommunity Medicine, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India, manipal.edu.ORCID https://orcid.org/0000-0002-7153-411X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our body is made up of many elements and compounds that work together to keep us healthy. Among them are trace elements, which are needed only in tiny amounts but play a very large role in protecting our cells from damage. When these trace elements are too low or too high, they can disturb the body's balance and may increase the risk of diseases such as oral cancer. In this study, we investigated how different trace elements are linked to early signs of oral cancer and precancerous conditions over the past 20 years. We reviewed studies available in the PubMed database that used elemental analysis to detect changes in oral tissues before cancer fully develops. Understanding how these trace elements affect oral health can help us shape better prevention policies. If we know which elements people in certain areas lack or have in excess, health authorities can design nutrition-based programs, awareness campaigns, and screening strategies to prevent oral cancer early. Linking science with public health policy can strengthen preventive oral care and help build a future where fewer people develop oral cancer.

Indexed as

elemental analysisgood health and well-beingoral canceroral potentially malignant disorderstrace elements

Identifiers

PMID42688796
PMCPMC13536907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.