ArticleJournal of dental sciences2026
Oral lichen planus possibly associated with Hashimoto's thyroiditis: A case-control study in a northwest Chinese population.
Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background/purpose: Some studies have previously demonstrated possible association between Hashimoto's thyroiditis (HT) and oral lichen planus (OLP), however, data of immunity and inflammation in these patients were not well investigated. This study aimed to propose some novel findings based on a case-control study of 185 OLP patients and 185 age- and gender-matched non-OLP volunteers in northwest China. Materials and methods: This study was designed and implemented in a tertiary teaching hospital between January 2021 and December 2024. Comprehensive evaluation was performed including thyroid function tests and seroimmunological parameters. Results: The incidence of HT among OLP patients reached 31.9 %, demonstrating a statistically significant elevation compared to the control group's prevalence of 9.7 % ( Conclusion: Our findings demonstrate a strong correlation between OLP, especially its erosive form, and thyroid autoimmunity, with female sex representing an independent and clinically relevant predisposing factor.
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