Evidence map›Paper›PMID 42688699›Full record

ArticleClinical case reports2026

A Rare Case of Cutaneous Metastasis From Oral Squamous Cell Carcinoma (OSCC) and the Possible Role of GALR2 as a Biomarker: A Case Report.

Ianny Brum Reis, Milena Moraes de Carvalho, Danilo Paschoal Ferrarezi, Natalie Aparecida Rodrigues Fernandes, Camyla Rodrigues Nascimento, Álvaro Formoso Pelegrini, Aldenora Maria Ximenes Rodrigues, Alex de Freitas Porsani, Flávio Ferlin Arbex, Carlos Rossa Junior

Abstract read
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In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ianny Brum ReisTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.ORCID https://orcid.org/0000-0002-2939-3501
Milena Moraes de CarvalhoTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.
Danilo Paschoal FerrareziTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.
Natalie Aparecida Rodrigues FernandesTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.
Camyla Rodrigues NascimentoTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.
Álvaro Formoso PelegriniTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.ORCID https://orcid.org/0000-0001-8163-8978
Aldenora Maria Ximenes RodriguesTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.
Alex de Freitas PorsaniSanta Casa Foundation Hospital of Araraquara Araraquara São Paulo Brazil.
Flávio Ferlin ArbexSanta Casa Foundation Hospital of Araraquara Araraquara São Paulo Brazil.
Carlos Rossa JuniorTumor Immunology Laboratory, Department of Diagnosis and Surgery São Paulo State University (UNESP), School of Dentistry Araraquara São Paulo Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a rare case of cutaneous metastasis from oral squamous cell carcinoma (OSCC). The primary tumor showed low expression of Galanin, CD68, GALR2, and Collagen IV, with increased FOXP3 and Vimentin. Systemic analysis revealed reduced CD8

Indexed as

distant metastasisGALR2immune responsemacrophage infiltrationneoplastic implant pattern

Identifiers

PMID42688699
PMCPMC13535119

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.