ArticleJournal of dental sciences2026
Effect of dental anxiety on the success of inferior alveolar nerve block in symptomatic irreversible pulpitis: A prospective clinical study.
Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Effectiveness of Buzzy BEE in Reducing Pain Perception During Inferior Alveolar Nerve Block in Children: A Split-Mouth Crossover Study.Children (Basel, Switzerland) · 2026Article
- Association of 4% Articaine with Profound Inferior Alveolar Nerve Block Success in Third Molar Surgery Performed by Dental Students: A Three-Anesthetic Observational Study.Dentistry journal · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Background/purpose: Successful anesthesia in symptomatic irreversible pulpitis (SIP) presents a clinical challenge, with psychological factors such as dental anxiety potentially affecting outcomes. This clinical trial aimed to evaluate dental anxiety's impact on the success of inferior alveolar nerve block (IANB) in mandibular molars diagnosed with SIP under standardized preoperative pain conditions. Materials and methods: In total, 52 systemically healthy patients with symptomatic irreversible pulpitis in mandibular first molars were included and categorized into low (MDAS ≤10) and moderate-to-high (MDAS ≥11) anxiety groups based on modified dental anxiety scale (MDAS) scores. All participants received IANB with 1.8 mL of 4 % articaine with epinephrine (1:100,000), followed by supplemental buccal-lingual infiltration. Anesthetic success was defined as a VAS score ≤3 during access cavity preparation. Salivary cortisol concentrations, pulse rate, and oxygen saturation were also recorded. The statistical analyses included independent t-tests, Pearson correlation, binary logistic regression, and multiple correspondence analysis. Results: Anesthesia success was significantly higher in the low anxiety group (84.2 %) than the high anxiety group (15.8 %) ( Conclusion: Dental anxiety was associated with lower success rates of local anesthesia in patients with SIP. Increased salivary cortisol levels were observed in anesthetic failures, indicating its potential relevance as a supportive biomarker; however, these findings should be interpreted with caution, considering that operator proficiency and technique also play critical roles in outcomes.
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