ReviewFrontiers in medicine2026
Ultrasound-indicated cerclage as a critical decision window in cervical insufficiency: a mini review of time-dependent risk interpretation.
Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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Abstract
Ultrasound-indicated cerclage occupies an intermediate position between history-based prophylaxis and emergency or physical examination-indicated cerclage. Current guidelines generally define this intervention by obstetric history and cervical-length thresholds, but these categorical criteria do not fully capture the time-dependent nature of cervical insufficiency. This focused Mini Review synthesizes international guidelines, randomized and meta-analytic evidence, and recent observational studies to examine ultrasound-indicated cerclage as a critical decision window within a dynamic process of cervical remodeling and progressive structural failure. In this framework, sonographic cervical shortening represents a transitional phase in which risk has become clinically visible but may still remain modifiable. Evidence most consistently supports cerclage in selected high-risk singleton pregnancies with prior spontaneous preterm birth or mid-trimester loss and current cervical shortening, whereas benefit is less certain in low-risk populations with an incidentally detected short cervix or after progression to membrane exposure or advanced dilation. Interpretation is limited by heterogeneity in patient selection, cervical state, timing of intervention, and reporting of operative variables. Reframing ultrasound-indicated cerclage as a time-dependent decision window may help explain heterogeneous findings, improve interpretation of guideline differences, and support more precise patient selection. Future studies should report cervical-length trajectory, gestational timing, cervical phenotype, membrane relationship, inflammatory context, and transition to emergency operative states.
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