Evidence map›Paper›PMID 42688623›Full record

ReviewWorld journal of otorhinolaryngology - head and neck surgery2026

Unveiling Otolith Mystery: Contemporary Testing Approaches and Their Clinical Significance.

Shun Zhou, E Tian, Hua-Jing Yang, Jun Wang, Zhao-Qi Guo, Jing-Yu Chen, Wan-Di Xu, Jia-Qi Guo, Zhang-Hong Zhou, Shi-Yu Shi and 7 more

Abstract readReview
In one paragraph

Review in World journal of otorhinolaryngology - head and neck surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Shun ZhouDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
E TianDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Hua-Jing YangDepartment of Ophthalmology, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Jun WangDepartment of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang China.ORCID https://orcid.org/0000-0002-4407-4445
Zhao-Qi GuoDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Jing-Yu ChenDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Wan-Di XuDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Jia-Qi GuoDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Zhang-Hong ZhouDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Shi-Yu ShiDepartment of Rehabilitation, Liyuan Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Xi-Xi YuDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Xin-Bo GaoDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Ni ZhaiDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.
Xin MaDepartment of Otorhinolaryngology, Head and Neck Surgery, People's Hospital Peking University Beijing China.
Qing ZhangDepartment of Otorhinolaryngology, Head and Neck Surgery, Xinhua Hospital Shanghai Jiaotong University School of Medicine Shanghai China.
Yi-Sheng LuDepartment of Physiology, School of Basic Medicine Huazhong University of Science and Technology Wuhan China.
Su-Lin ZhangDepartment of Otorhinolaryngology, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China.ORCID https://orcid.org/0000-0002-3609-6804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Otolith is a critical component of the peripheral vestibular system responsible for detecting linear acceleration. Dysfunction of the otolith organs can lead to vertigo, balance disturbances, and gaze instability. By elucidating the physiological foundations and evaluating both current and emerging methods for assessing otolith function, this review aims to provide a comprehensive resource for researchers and clinicians in the field of vestibular science, contributing to improved diagnostic accuracy and the development of more effective therapeutic strategies. Data Sources: The databases of PubMed, Embase, and Cochrane Library were systematically searched for the articles. Methods: The information of physiological mechanism and clinical significance were extracted from each article. Results: Vestibular-evoked myogenic potentials (VEMPs) are valuable for evaluating saccule and utricle function, with clinical applications in diagnosing several diseases. Subjective visual vertical (SVV) has clinical value in the diagnosis of peripheral and central vestibular diseases, with recent advancements in smartphone Apps and VR devices providing more accessibility. The ocular counter-roll (OCR) examination has a superior application prospect, but standardization including the normal range and duration of recovery, was incomplete. The off-vertical axis rotation (OVAR) can be used to explore motion sickness. The test of linear acceleration perception is limited by device, site and result instability, so it is difficult to apply clinically. Balance-related tests have been applied clinically, but the isolation of otolith components that determine balance is an unfinished task. Conclusion: The review emphasizes the need for more precise and standardized otolith function tests to enhance diagnostic accuracy and therapeutic strategies, ultimately improving patient outcomes in vestibular disorders.

Indexed as

functional testotolithsacculeSVVutricleVEMP

Identifiers

PMID42688623
PMCPMC13535002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.