Evidence map›Paper›PMID 42688565›Full record

SynthesisFrontiers in medicine2026

Apolipoprotein L1 risk genotypes and odds of lupus nephritis-associated kidney failure in systemic lupus erythematosus: a systematic review and meta-analysis.

Silvia E Aldana-Pérez, Alex Dominguez-Vargas, Gustavo Aroca-Martinez, Ana Moreno-Woo, Luis Fang, Gloria Garavito De Egea, Eduardo Egea Bermejo, Henry J González-Torres

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia E Aldana-PérezCentro de Investigaciones en Ciencias de la Vida, Facultad de Ciencias de la Salud, Universidad Simón Bolívar, Barranquilla, Colombia.
Alex Dominguez-VargasData Analysis and Mining Department, D&P Consulting Service SAS, Barranquilla, Colombia.
Gustavo Aroca-MartinezCentro de Investigaciones en Ciencias de la Vida, Facultad de Ciencias de la Salud, Universidad Simón Bolívar, Barranquilla, Colombia.
Ana Moreno-WooDivisión Ciencias de la Salud, Universidad del Norte, Barranquilla, Colombia.
Luis FangDivisión Ciencias de la Salud, Universidad del Norte, Barranquilla, Colombia.
Gloria Garavito De EgeaDivisión Ciencias de la Salud, Universidad del Norte, Barranquilla, Colombia.
Eduardo Egea BermejoDivisión Ciencias de la Salud, Universidad del Norte, Barranquilla, Colombia.
Henry J González-TorresCentro de Investigaciones en Ciencias de la Vida, Facultad de Ciencias de la Salud, Universidad Simón Bolívar, Barranquilla, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Systemic lupus erythematosus (SLE) is characterized by a prominent interferon signature that upregulates apolipoprotein L1 ( Methods: We conducted a systematic review and meta-analysis of observational studies to evaluate the association between Results: Four observational studies comprising a total of 1,885 patients of African ancestry were included. Of these, 321 carried high-risk Conclusion: High-risk Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD42024587943, identifier PROSPERO (CRD42024587943).

Indexed as

APOL1end-stage renal diseasegenetic associationlupus nephritisrenal prognosis

Identifiers

PMID42688565
PMCPMC13534799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.