Evidence map›Paper›PMID 42688523›Full record

ReviewSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2026

[Research Advances on the Role of the Oral Microbiota in Age-Related Homeostatic Dysregulation and Systemic Diseases].

Zhuojia He, Dongliang Li, Xian Peng

Abstract readReviewEnglish Abstract
In one paragraph

Review in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhuojia He( 610041)State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0009-0002-9240-1487
Dongliang Li( 610041)State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Xian Peng( 610041)State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.ORCID 0000-0001-8479-5944

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The regulatory role of the microbiota in the aging process has increasingly attracted attention. As a crucial microbial ecosystem of the human body, the oral microbiota plays a unique role in maintaining host health and contributing to disease development. This review summarizes the dynamic changes in specific oral microbial genera under both healthy and diseased conditions, analyzes the impact of age-related physiological alterations of the oral cavity on the microbiota, and comprehensively elucidates the mechanisms by which age-associated oral microbial dysbiosis participates in oral and systemic diseases. Given the close interplay between the oral microbiota and aging, its significance in promoting healthy aging has become increasingly prominent. Investigating the succession patterns of the oral microbiota not only helps to unravel the mechanisms underlying the high incidence of systemic diseases in the elderly, but also provides a theoretical basis for developing microbiota-based intervention strategies and identifying novel early-biomarkers for healthy aging.

Indexed as

AgingDysbiosisHomeostasisMicrobiotaMouthHumansAgingDiseaseDysbiosisHealthy agingOral cavityReview

Identifiers

PMID42688523
PMCPMC13534503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.