ArticleIJU case reports2026
Immune-Checkpoint-Inhibitor-Related Bullous Pemphigoid During Avelumab Maintenance Therapy in a Patient With Metastatic Renal Pelvic Carcinoma: A Case Report.
Article in IJU case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Introduction: Bullous pemphigoid is a rare cutaneous, immune-related adverse event, and avelumab-associated cases are extremely rare. Case Presentation: A 76-year-old man receiving avelumab maintenance therapy for recurrent renal pelvic carcinoma developed pruritic erythema and tense blisters 20 days after the first dose. Laboratory examination showed eosinophilia, increased immunoglobulin E level, and markedly elevated anti-BP180 antibodies. Moreover, skin biopsy revealed subepidermal blistering with eosinophilic infiltration, supporting drug-associated bullous pemphigoid. Prednisolone (15 mg/day, increased to 25 mg/day) led to marked improvement. After the second course, avelumab was discontinued, and no recurrence occurred. Conclusion: Immune-checkpoint-inhibitor-related, drug-associated bullous pemphigoid can present with nonspecific symptoms before blistering. Thus, urologists should monitor skin changes during immune checkpoint inhibitor therapy and promptly involve dermatology.
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