Evidence map›Paper›PMID 42688399›Full record

ArticleFrontiers in medicine2026

Pixel shift-based reversible steganography for privacy-preserving medical images.

Xiaofeng Huang, Bing Zhang, Xishun Zhu

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaofeng HuangSchool of Mathematics and Statistics, Hainan Normal University, Haikou, China.
Bing ZhangSchool of Intelligent Manufacturing, Nanyang Institute of Technology, Nanyang, Henan, China.
Xishun ZhuSchool of Mathematics and Statistics, Hainan Normal University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steganography plays a critical role in preserving the privacy of medical images by protecting sensitive patient information without compromising image quality or diagnostic utility. This paper proposes a novel lossless privacy protection algorithm for medical images based on pixel displacement. The core innovation lies in the synergistic combination of physical transformation and deep learning-specifically, the integration of shift-rectification with a dual-carrier embedding mechanism. The proposed method begins by applying byte-level pixel shifting to the confidential medical image to generate a shift-rectified version. A deep convolutional neural network is then employed to embed both the original and the rectified medical images into two separate carrier images, ensuring that the resulting container images are visually indistinguishable from the carriers. Subsequently, a dedicated recovery network extracts and reconstructs the lossy shift-rectified image and a degraded version of the original from the two carriers, using the former to calibrate and fully restore the original medical image in a lossless manner. Experimental results demonstrate the algorithm's effectiveness in preserving privacy while enabling perfect image recovery: the container images achieve an average PSNR of 40.08 dB and MSSIM of 0.988 relative to the carriers, confirming near-perceptual-indistinguishability; the reconstructed secret images are recovered with a bit-level accuracy of 100%; and the algorithm maintains robustness under Gaussian noise, salt-and-pepper noise, and PCA compression with lossless recovery guaranteed. Moreover, the method shows excellent generalization across multiple medical imaging datasets (CT, MRI, and X-ray), highlighting its clinical applicability and innovation in secure medical image transmission systems.

Indexed as

ablation studybit error rateimage hidinglosslessprivacy protectionrecurrent codes

Identifiers

PMID42688399
PMCPMC13534072

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.