Evidence map›Paper›PMID 42688380›Full record

ArticleFrontiers in public health2026

From screening to enrollment drop-offs: perspectives of minoritized participants in Indiana.

Sylk Sotto-Santiago, Cynthia Brown, Brownsyne Tucker Edmonds, Cynthia Ziwawo, Molly Frank, Brenda Hudson, Sarah E Wiehe

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sylk Sotto-SantiagoDepartment of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Cynthia BrownDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
Brownsyne Tucker EdmondsIndiana Clinical and Translational Sciences Institute, Indianapolis, IN, United States.
Cynthia ZiwawoDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
Molly FrankDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, United States.
Brenda HudsonIndiana Clinical and Translational Sciences Institute, Indianapolis, IN, United States.
Sarah E WieheIndiana Clinical and Translational Sciences Institute, Indianapolis, IN, United States.

Funding

Indiana Clinical and Translational Sciences InstituteUM1TR004402 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI Sharon M Moe, Sarah Elizabeth Wiehe · 2023 to 2026
$21.6M
NCATS NIH HHS UM1 TR004402
6 · The paper itself

Abstract

Vaccine uptake among Black and Latine populations remains persistently lower than among white populations, yet drop-offs between screening and enrollment in clinical trials is underexamined. The current sociopolitical moment, marked by "DEI" rollbacks, disruptions of federally funded health research, and sensitivity to health equity language, heightens the urgency of this work and threatens infrastructure supporting equitable recruitment. This qualitative study investigated non-enrollment among individuals positively screened for a vaccine trial at Indiana University School of Medicine and the Indiana Clinical and Translational Sciences Institute. Seven themes emerged: institutional reputation; communication and awareness; healthcare professionals' role; public and community engagement; recruitment practices; research participant motivation; and barriers to enrollment. From a critical lens, the findings of this study make clear that closing the gap between interest and enrollment in clinical trials requires more than improved recruitment messaging but structural transformation within every step.

Indexed as

Clinical Trials as TopicPatient SelectionBlack or African AmericanCOVID-19FemaleHispanic or LatinoHumansIndianaMaleMotivationQualitative Researchclinical trialsCOVID-19diversitypublic healthrecruitmentvaccine

Identifiers

PMID42688380
PMCPMC13534968

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.