Evidence map›Paper›PMID 42688369›Full record

ArticleFrontiers in neuroscience2026

Morphine-induced

Michael Swingler, Martina Donadoni, Senem Cakir, Muhammed Bishir, Wenfei Huang, Sulie L Chang, Ilker K Sariyer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael SwinglerDepartment of Microbiology, Immunology, and Inflammation, Center for Neurovirology and Gene Editing, Temple University Lewis Katz School of Medicine, Philadelphia, PA, United States.
Martina DonadoniDepartment of Microbiology, Immunology, and Inflammation, Center for Neurovirology and Gene Editing, Temple University Lewis Katz School of Medicine, Philadelphia, PA, United States.
Senem CakirDepartment of Microbiology, Immunology, and Inflammation, Center for Neurovirology and Gene Editing, Temple University Lewis Katz School of Medicine, Philadelphia, PA, United States.
Muhammed BishirInstitute of NeuroImmune Pharmacology, Seton Hall University, South Orange, NJ, United States.
Wenfei HuangInstitute of NeuroImmune Pharmacology, Seton Hall University, South Orange, NJ, United States.
Sulie L ChangInstitute of NeuroImmune Pharmacology, Seton Hall University, South Orange, NJ, United States.
Ilker K SariyerDepartment of Microbiology, Immunology, and Inflammation, Center for Neurovirology and Gene Editing, Temple University Lewis Katz School of Medicine, Philadelphia, PA, United States.

Funding

Viral Gene Editing and Bioinformatics Core for Institution # 269291P30MH092177 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI Ilker Kudret Sariyer · 2011 to 2026
$24.9M
Gene editing strategies to target HIV for elimination in periphery and brainR01MH110360 · NIMH · DREXEL UNIVERSITY · PI Ilker Kudret Sariyer, Brian Wigdahl · 2016 to 2026
$7.3M
Modulation of OPRM1 alternative splicing by morphine and HIV-1 NefR01DA052284 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI CHANG, SULIE L., SARIYER, ILKER KUDRET · 2021 to 2025
$1.7M
NIDA NIH HHS R01 DA052284NIMH NIH HHS P30 MH092177NIMH NIH HHS R01 MH110360
6 · The paper itself

Abstract

Clinically used opioids, such as morphine, primarily act through the

Indexed as

alternative splicingcerebral organoidsdependenceIPA analysisMOR-1MOR-1XopioidsOPRM1

Identifiers

PMID42688369
PMCPMC13534043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.