Evidence map›Paper›PMID 42688282›Full record

ReviewSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2026

[Systemic Reprogramming of Cellular Senescence: Coordinated Regulation of Metabolism, Epigenetics, and Proteostasis].

Yulin Zheng, Qian Liu, Ruihong Wang, Chongkui Sun

Abstract readReviewEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Review in Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yulin Zheng•（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China.ORCID 0009-0002-1287-6475
Qian Liu•（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China.
Ruihong Wang•（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China.
Chongkui Sun•（） （ 610072）Department of Geriatric Cardiology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (Affiliated Hospital of University of Electronic Science and Technology of China), Chengdu 610072, China.ORCID 0000-0003-0362-4129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular senescence has long been considered an irreversible process. However, recent breakthroughs in partial cellular reprogramming have demonstrated that senescent cells maintain a metastable state amenable to resetting. This review outlines a systemic framework for anti-aging interventions that integrate three core dimensions. First, metabolic reprogramming through the elevation of nicotinamide adenine dinucleotide (NAD

Indexed as

Cellular ReprogrammingCellular SenescenceEpigenesis, GeneticProteostasisAnimalsHumansKruppel-Like Factor 4Metabolic ReprogrammingNADKLF4 protein, humanKruppel-Like Factor 4NADAgingCellular reprogrammingEpigeneticsNicotinamide adenine dinucleotideProteostasis

Identifiers

PMID42688282
PMCPMC13534517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.