Evidence map›Paper›PMID 42688269›Full record

ArticleFrontiers in bioengineering and biotechnology2026

Single-baseline virtual progression modeling of Crowe type I-III developmental dysplasia of the hip: a finite element study of stress-location migration.

Heng Zhang, Xuanhao Zhang, Jiajun Wu, Boyu Long, Yixuan Li, Wenze Zhang, Yu Chen, Bowen Li

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Article in Frontiers in bioengineering and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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8 authors.

Heng Zhang *Department of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University, Bengbu, Anhui, China.
Xuanhao Zhang *The First School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, China.
Jiajun WuDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University, Bengbu, Anhui, China.
Boyu Long *The First School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, China.
Yixuan LiThe First School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, China.
Wenze ZhangThe First School of Clinical Medicine, Bengbu Medical University, Bengbu, Anhui, China.
Yu ChenDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University, Bengbu, Anhui, China.
Bowen LiDepartment of Orthopedics, The First Affiliated Hospital of Bengbu Medical University, Anhui Key Laboratory of Tissue Transplantation, Bengbu Medical University, Bengbu, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Developmental dysplasia of the hip alters acetabular morphology and load transfer, but classification-related changes in local stress distribution remain incompletely understood. Methods: A Crowe type I finite element model was directly reconstructed from one patient's pelvic computed tomography data. Crowe type II and III models were subsequently generated from the same anatomical baseline as standardized, classification-consistent virtual morphologies rather than independent patient-specific cases. This single-baseline, internally controlled design was used to reduce inter-individual anatomical variability and evaluate morphology-related changes in stress distribution and load-transfer pathways. A simplified 600 N axial load was applied to compare peak von Mises stress and stress distribution in the acetabular-side pelvic bone, acetabular/pseudoacetabular cartilage, proximal femur, and femoral head cartilage. To assess the influence of the simplified loading assumption, an additional loading-sensitivity analysis was performed using a 1,888 N resultant force inclined medially by 16° from the global vertical direction in the frontal plane. Results: Peak stress within the acetabular-side pelvic bone region increased from Crowe type I to III (2.41, 5.79, and 6.71 MPa, respectively), whereas acetabular/pseudoacetabular cartilage stress peaked in type II (3.54 MPa). Femoral head cartilage stress increased progressively from 1.23 MPa in type I to 2.08 MPa in type II and 3.42 MPa in type III. High-stress regions migrated from the superior true acetabulum to the true acetabulum-pseudoacetabulum transition region and then to the localized pseudoacetabular load-bearing region. Under the alternative loading scenario, the principal classification-dependent stress relationships and pelvic-side stress-location migration pattern were maintained. Material-property sensitivity analyses produced peak-stress changes of no more than 2.46% and similarly preserved these patterns. Conclusion: Across the standardized Crowe type I-III virtual models, increasing classification severity was associated not only with changes in stress magnitude but also with spatial migration of the principal load-bearing regions. These findings provide an internally controlled biomechanical reference for understanding classification-related load-transfer patterns but should not be interpreted as patient-specific predictions or population-level stress thresholds. Independent patient datasets are required to validate these hypothesis-generating observations before clinical application.

Indexed as

biomechanicscrowe classificationdevelopmental dysplasia of the hipfinite element analysisstress-location migrationvirtual progression modeling

Identifiers

PMID42688269
PMCPMC13533989

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