Evidence map›Paper›PMID 42688005›Full record

ArticleFrontiers in cellular and infection microbiology2026

Severe co-infection with influenza A virus H3N2 and community-acquired methicillin-susceptible

Zhangyan Guo, Haifeng Qi, Qian Zhang, Yi Wang, Yanqiang Du

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhangyan Guo *Department of Pediatric Intensive Care Unit of Xi'an Children's Hospital, National Children's Regional Medical Center (Northwest), Children's Hospital of Xi'an Jiaotong University, Xi'an, China.
Haifeng Qi *Department of Pediatric Intensive Care Unit of Xi'an Children's Hospital, National Children's Regional Medical Center (Northwest), Children's Hospital of Xi'an Jiaotong University, Xi'an, China.
Qian ZhangDepartment of Pediatric Intensive Care Unit of Xi'an Children's Hospital, National Children's Regional Medical Center (Northwest), Children's Hospital of Xi'an Jiaotong University, Xi'an, China.
Yi WangDepartment of Pediatric Intensive Care Unit of Xi'an Children's Hospital, National Children's Regional Medical Center (Northwest), Children's Hospital of Xi'an Jiaotong University, Xi'an, China.
Yanqiang DuDepartment of Pediatric Intensive Care Unit of Xi'an Children's Hospital, National Children's Regional Medical Center (Northwest), Children's Hospital of Xi'an Jiaotong University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Influenza co-infection with Case presentation: We report an 8-year-4-month-old male with influenza A (H3N2) who developed septic shock and refractory hypoxemia, requiring immediate intubation. Due to persisting respiratory failure despite maximal ventilation, veno-venous extracorporeal membrane oxygenation (VV-ECMO) was initiated on day 1. Metagenomic next-generation sequencing identified Conclusion: This case underscores that during influenza seasons, early empirical anti-staphylococcal therapy should be considered in children with rapidly progressive pneumonia and shock, even when CA-MSSA is suspected. Additionally, routine lactate monitoring is critical during linezolid therapy to enable prompt recognition and management of life-threatening LILA.

Indexed as

CoinfectionInfluenza A Virus, H3N2 SubtypeInfluenza, HumanPneumonia, NecrotizingRespiratory Distress SyndromeShock, SepticStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsCommunity-Acquired InfectionsCommunity-Acquired PneumoniaExtracorporeal Membrane OxygenationHumansLinezolidMalePneumonia, StaphylococcalAnti-Bacterial AgentsLinezolidcase reportextracorporeal membrane oxygenationinfluenzanecrotizing pneumoniapediatricsStaphylococcus aureus

Identifiers

PMID42688005
PMCPMC13533659

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.