ArticleResearch square2026
Combined effects of bacterial vaginal colonization and HIV on pregnancy outcomes: A Systematic Review and Meta-analysis.
Article in Research square, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Authors and funding
8 authors.
Funding
Abstract
The independent effects of HIV and bacterial vaginal colonization on adverse pregnancy outcomes are well established and may be exacerbated by increasing antimicrobial resistance (AMR). However, their combined association with pregnancy outcomes has not been comprehensively evaluated. We conducted a systematic review and meta-analysis to assess the joint effects of HIV and vaginal bacterial colonization on birth weight, preterm birth (PTB), and AMR. MEDLINE, EMBASE, CINAHL, Scopus, Web of Science, Cochrane Library, African Journals Online, and PubMed were searched for observational studies published through December 31, 2023. Eligible studies reported vaginal bacterial colonization stratified by HIV status and pregnancy outcomes. Study quality was assessed using the Newcastle-Ottawa Scale, and pooled odds ratios (ORs) were estimated using random-effects models. Thirteen studies involving 5,807 pregnant women were included. The pooled prevalence of bacterial vaginal colonization was 26% (95% CI: 17.3-37.4%; I
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