SynthesisFrontiers in neurology2026
MRI features of parenchymal neuro-Behçet's disease: a systematic review and meta-analysis.
Synthesis in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Glymphatic dysfunction as a potential mechanistic link to cognitive ımpairment in Behçet's disease: a hypothesis.Rheumatology international · 2026Article
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12 authors.
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Abstract
Introduction: Magnetic resonance imaging (MRI) is essential for diagnosing neuro-Behçet's disease (NBD). The classic MRI sign typically results from parenchymal NBD lesions in the thalamus, midbrain, and the internal capsule. It may also affect the spinal cord, bilateral basal ganglia, pons, and white matter. Despite its importance, a comprehensive quantitative synthesis of MRI characteristics differentiating NBD subtypes is still needed. This study aimed to compare specific MRI findings, such as brainstem atrophy, enhancing lesions, and anatomical distribution, in acute and chronic progressive parenchymal NBD, with potential implications for prognosis and long-term disease management. Methods: This systematic review and meta-analysis was conducted according to the PRISMA 2020 guidelines. PubMed, Web of Science, and Scopus were searched from inception to August 2025. Retrospective studies assessing the MRI findings of parenchymal NBD were included. Results: Seven retrospective studies (total Conclusion: Our analysis provides quantitative evidence for distinct MRI characteristics, such as differential brainstem atrophy and enhanced lesion incidence, which may inform NBD subtyping and have implications for prognosis and long-term disease management. However, this meta-analysis is limited by the retrospective nature of the included studies and their potential heterogeneity, necessitating further prospective research to confirm these findings. Systematic review registration: PROSPERO, CRD420251178483.
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