Evidence map›Paper›PMID 42687929›Full record

ArticleFrontiers in nutrition2026

Adherence to the Mediterranean diet and incident cardiovascular outcomes among older adults.

Emanuele Marzetti, Riccardo Calvani, Isabel Rodriguez-Sanchez, Samuel da Silva Aguiar, Anna Picca, Matteo Tosato, Stefano Cacciatore, Francesco Landi, Helio José Coelho Júnior

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emanuele MarzettiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Riccardo CalvaniFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Isabel Rodriguez-SanchezDepartment of Geriatrics, Hospital Universitario Clínico San Carlos, Madrid, Spain.
Samuel da Silva AguiarPostgraduate Program in Physical Education, Catholic University of Brasília, Brasília, Brazil.
Anna PiccaFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Matteo TosatoFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Stefano CacciatoreDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL, United States.
Francesco LandiFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Helio José Coelho JúniorFondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The present study examined the prospective associations between adherence to the Mediterranean (MED) diet, its individual components, and incident cardiovascular disease (CVD) among community-dwelling older adults. Methods: Data were obtained from the English Longitudinal Study of Ageing (ELSA). Participants aged ≥65 years without hypertension at baseline (Wave 9, 2018-2019) were followed through Wave 11 (2023-2024). Adherence to the MED diet was assessed using the Medi-Lite score. Incident hypertension, myocardial infarction, and stroke were identified through self-reported physician diagnoses. Logistic regression analyses were performed to examine the prospective associations between MED diet adherence, individual dietary components, and cardiovascular outcomes, adjusting for age, sex, and caloric intake. Results: A total of 338 participants (74.6 ± 6.2 years; 56.6% women) were included. During follow-up, the incidence of hypertension, myocardial infarction, and stroke was 12.4%, 2.6%, and 2.6%, respectively. No statistically significant associations were detected between overall MED diet adherence and incident hypertension (OR = 0.992, 95% CI = 0.586-1.679), myocardial infarction (OR = 1.422, 95% CI = 0.381-5.302), or stroke (OR = 0.808, 95% CI = 0.360-1.811). Likewise, none of the individual MED diet components was significantly associated with incident CVD outcomes. Conclusion: In conclusion, no statistically significant associations were detected between adherence to the MED diet and incident CVD among community-dwelling older adults in England. However, given the relatively low number of cardiovascular events, particularly myocardial infarction and stroke, these findings should be interpreted with caution. Further studies with longer follow-up periods and larger numbers of CVD events are warranted to provide more precise estimates and further clarify these associations.

Indexed as

diet patternheart attackhypertensionmalnutritionmyocardial infarctionstroke

Identifiers

PMID42687929
PMCPMC13533671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.