Evidence map›Paper›PMID 42687186›Full record

ReviewPopulation health metrics2026

Excess mortality and associated sociodemographic factors during the COVID-19 pandemic in rural Pune Maharashtra, India: a retrospective data analysis from the Vadu health and demographic surveillance system.

Uddhavi Kand, Chodziwadziwa Kabudula, Bharat Choudhari, Tapas Kumar Mohanty, Sandeep Bhujbal, Arunkumar Gondhali, Jean J H Bashingwa, Beth A Tippett Barr, Stephen Tollman, Sanjay Juvekar and 2 more

Abstract readReview
In one paragraph

Review in Population health metrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Uddhavi KandVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Chodziwadziwa KabudulaUniversity of the Witwatersrand, Johannesburg, South Africa.
Bharat ChoudhariVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Tapas Kumar MohantyVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Sandeep BhujbalVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Arunkumar GondhaliVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Jean J H BashingwaUniversity of the Witwatersrand, Johannesburg, South Africa.
Beth A Tippett BarrNyanja Health Research Institute, Salima, Malawi.
Stephen TollmanUniversity of the Witwatersrand, Johannesburg, South Africa.
Sanjay JuvekarVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Anand KawadeVadu Rural Health Program, KEM Hospital Research Centre, Pune, India.
Dhiraj AgarwalVadu Rural Health Program, KEM Hospital Research Centre, Pune, India. dhiraj.agarwal@kemhrcvadu.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBetween January 2020 and August 2023, India documented over 450 million confirmed cases of COVID-19 and nearly 0.5 million COVID-19 deaths. While reported mortality rates in India appeared lower than expected, the actual mortality may be higher due to underreporting and disparities in healthcare access. This study aimed to compare mortality before and during the COVID-19 pandemic and identify associated socio-demographic factors in rural Pune, Maharashtra, India using longitudinal population-based data from the Vadu Health and Demographic Surveillance System.

methodsIndividual and mortality data from the Vadu HDSS, India were collected from 2018 to 2021. Descriptive analyses were conducted to examine the variation in mortality by sociodemographic factors during pre-COVID-19 [2018-2019] and COVID-19 [2020-2021] periods. Cox regression with hazard ratios [HR] and 95% confidence intervals [CI] were used to measure the association between socio-demographic factors and mortality.

resultsThere were 2039 deaths that occurred between 2018 and 2021, of which 40.6% [828/2039] were female. The overall risk of mortality increased during COVID-19 [HR1.2,95%CI:1.1-1.3], but this varied by sociodemographic characteristics. The risk of death was greater [HR1.8,95%CI:1.5-2.2] among individuals living in single-person households compared to those living in 2-5 member households, and there was a strong trend of increased mortality risk with older age. Widowed individuals had a greater risk of mortality than those who were married [HR2.1,95%CI:1.9-2.4]. Education was strongly protective against mortality; those who had any level of education had a lower risk of dying than those with no education [HR0.4,95%CI:0.3-0.5].

conclusionIncreased COVID-19 mortality in India was associated with older age, widowhood, and living alone. These findings highlight the need for targeted vaccination, early clinical care, and community outreach for vulnerable populations during future pandemics.

Indexed as

COVID-19MortalityRural PopulationSociodemographic FactorsAdolescentAdultAgedChildChild, PreschoolFemaleHumansIndiaMaleMiddle AgedPandemicsPopulation SurveillanceCOVID-19 mortalityHDSSIndiaSocio-demographic factors

Identifiers

PMID42687186
PMCPMC13536605

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.