Evidence map›Paper›PMID 42686903›Full record

ArticleNature2026

Structure and operating principles of a monkeypox virus replisome.

Zishuo Yu, Pradeep Sathyanarayana, Joel M J Tan, Side Hu, Xiaoyi Fan, Angela Gao, Philip J Kranzusch, Joseph J Loparo, Jonathan Abraham

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zishuo YuDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.
Pradeep SathyanarayanaDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Joel M J TanDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6051-3786
Side HuDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.
Xiaoyi FanDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0009-0002-3181-9994
Angela GaoDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0009-0002-7149-9841
Philip J KranzuschDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-4943-733X
Joseph J LoparoDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-4941-4696
Jonathan AbrahamDepartment of Microbiology, Harvard Medical School, Boston, MA, USA. jonathan_abraham@hms.harvard.edu.ORCID http://orcid.org/0000-0002-7937-3920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poxviruses are double-stranded DNA viruses with large genomes. Among them, monkeypox virus (MPXV) has been responsible for two recent public health emergencies as declared by the World Health Organization

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.