ArticleScientific reports2026
A retrospective study of mandibular incisor intrusion with invisalign in adult deep-bite patients.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This retrospective study quantitatively evaluated mandibular incisor intrusion and associated vertical skeletal changes during deep-bite correction using Invisalign clear aligner therapy. Twenty-seven adult patients (19-54 years of age) with skeletal Class I or II malocclusion and deep overbite (> 3 mm) treated with Invisalign incorporating precision bite ramps were retrospectively analyzed. Lateral cephalometric radiographs obtained before (T0) and after treatment (T1) were superimposed on the cranial base and mandible. Mandibular incisor movement was assessed using centroid-based measurements to isolate pure intrusion and minimize the influence of tipping. Changes in the occlusal plane angle, mandibular plane angle (FMA), incisor mandibular plane angle (IMPA), and molar vertical position were also evaluated. Paired t-tests were performed for statistical comparisons. The mandibular incisor centroid demonstrated statistically significant pure intrusion of 1.63 mm (p < 0.001). Occlusal plane angle increased significantly (mean change: 2.38°, p = 0.001) and overbite decreased (mean change: -1.98 mm, p = 0.001), whereas changes in the FMA, IMPA, and mandibular molar extrusion were not statistically significant, suggesting limited vertical skeletal changes during treatment. These findings suggest that Invisalign therapy with precision bite ramps demonstrated mandibular incisor intrusion in adult deep-bite patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.