ArticleNature nanotechnology2026
Dynamic biomass micro-nanofibre framework for entrapment and clearance of gastrointestinal microplastics.
Yang Wu, Fangtian Liu, Yifei Liu, Min Zheng, Jiacheng Sun, Xiaowen Shi, Jun Wu, Yumin Du, Hongbing Deng, Xue Zhou
Abstract read
In one paragraphArticle in Nature nanotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
10 authors.
Yang Wu *Hubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China.ORCID http://orcid.org/0000-0003-2774-5996 Fangtian Liu *Hubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China.
Yifei LiuHubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China.
Min ZhengHubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China.
Jiacheng SunDepartment of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiaowen ShiHubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China.ORCID http://orcid.org/0000-0001-8294-2920 Jun WuDepartment of Cardiology, Renmin Hospital of Wuhan University, Hubei Key Laboratory of Autonomic Nervous System Modulation, Cardiac Autonomic Nervous System Research Center of Wuhan University, Cardiovascular Research Institute, Wuhan University, Hubei Key Laboratory of Cardiology, Wuhan, China. wj@whu.edu.cn.ORCID http://orcid.org/0009-0005-4489-3001 Yumin DuHubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China.
Hongbing DengHubei Key Laboratory of Biomass Resource Chemistry and Environmental Biotechnology, Hubei International Scientific and Technological Cooperation Base of Sustainable Resource and Energy, School of Resource and Environmental Science, Wuhan University, Wuhan, China. hbdeng@whu.edu.cn.ORCID http://orcid.org/0000-0002-9784-6138 Xue ZhouDepartment of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. xue.zhou@hust.edu.cn.ORCID http://orcid.org/0000-0002-8254-9341 Funding
National Natural Science Foundation of China (National Science Foundation of China) 52173061National Natural Science Foundation of China (National Science Foundation of China) 52203069National Natural Science Foundation of China (National Science Foundation of China) 52373062National Natural Science Foundation of China (National Science Foundation of China) 52573122
6 · The paper itselfAbstract
Microplastics (MPs) are infiltrating global food systems, where they disseminate systemically, posing unmet health risks as current strategies fail to prevent bioaccumulation. We have engineered an oral alginate-chitin micro-nanofibre framework (Alg-Ch) as a pH-responsive scavenger, which was formed via lyophilization-induced hydrogen bonding and physical entanglement between alginate microfibres and chitin nanofibrous sheets (1:10 ratio). Alg-Ch captured MPs predominantly through two mechanisms: electrostatic adsorption onto a protonated chitin nanonetwork in gastric acid, and physical entrapment by swollen alginate at intestinal pH. It captured 500-nm spherical MPs of varying surface chemistry (polystyrene (PS), PS-COOH, PS-NH
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