Evidence map›Paper›PMID 42686843›Full record

ArticleSurgical endoscopy2026

Minimally invasive versus open liver resection for hepatic alveolar echinococcosis within a disease-control oriented surgical strategy: a single-center retrospective study.

Akihisa Nagatsu, Tatsuhiko Kakisaka, Shunsuke Shichi, Yuzuru Sakamoto, Sunao Fujiyoshi, Takeshi Aiyama, Norio Kawamura, Masaaki Watanabe, Ryoichi Goto, Akinobu Taketomi

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Akihisa NagatsuDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Tatsuhiko KakisakaDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan. puripurikoyu@gmail.com.ORCID http://orcid.org/0000-0002-8556-5945
Shunsuke ShichiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Yuzuru SakamotoDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Sunao FujiyoshiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Takeshi AiyamaDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Norio KawamuraDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Masaaki WatanabeDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Ryoichi GotoDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.
Akinobu TaketomiDepartment of Gastroenterological Surgery I, Graduate School of Medicine, Hokkaido University, North 15 West 7, Kita-Ku, Sapporo, 060-8638, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe surgical strategy for hepatic alveolar echinococcosis (AE) differs from that for typical malignant tumors, as treatment is not solely determined by the feasibility of complete (R0) resection. While complete resection remains the preferred goal, cytoreductive surgery combined with albendazole therapy is considered in selected cases. The role of minimally invasive surgery (MIS) within this disease-control oriented strategy remains unclear.

methodsWe retrospectively analyzed 126 patients who underwent liver resection for hepatic AE between January 2010 and March 2026: 87 underwent open surgery and 39 underwent MIS. Perioperative and disease-control outcomes were compared, with propensity score overlap weighting used to adjust for baseline differences.

resultsThe MIS group had smaller lesions and less advanced disease. Operative time was similar, whereas blood loss, Clavien-Dindo grade ≥II morbidity, severe morbidity, and hospital stay were lower in the MIS group. After overlap weighting, MIS was not associated with an increased hazard of disease progression (hazard ratio 0.47, 95% confidence interval 0.07-3.22; p=0.44). An adjusted hazard ratio for overall survival was not estimable because no deaths occurred in the MIS group.

conclusionsIn selected patients with hepatic AE, MIS was associated with favorable perioperative outcomes. Although no increased risk of disease progression was detected after adjustment, limited events and shorter follow-up preclude conclusions regarding long-term equivalence.

Indexed as

Disease controlHepatectomyHepatic alveolar echinococcosisLaparoscopic liver resectionMinimally invasive surgeryRobotic liver resection

Identifiers

PMID42686843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.