Evidence map›Paper›PMID 42685680›Full record

ReviewCell transplantation

Stem cell strategies for cell replacement therapy in endocrine diseases.

Chengjia Mi, Xie Cheng, JinYang Tang, Yang Gao, Jing Zhang, Yan Yang, Guixiang Tan, Chunbing Zheng, Haisong Liu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chengjia MiSchool of Biomedical Sciences, Hunan University, Changsha, Hunan, China.ORCID 0009-0009-4746-8608
Xie ChengSchool of Biomedical Sciences, Hunan University, Changsha, Hunan, China.
JinYang TangSchool of Biomedical Sciences, Hunan University, Changsha, Hunan, China.
Yang GaoSchool of Biomedical Sciences, Hunan University, Changsha, Hunan, China.
Jing ZhangSchool of Biomedical Sciences, Hunan University, Changsha, Hunan, China.
Yan YangAdvanced Institute for Ocean Research, Southern University of Science and Technology, Shenzhen, China.
Guixiang TanR&D Department, Changsha Institute of Industrial Technology for Stem Cell and Regenerative Medicine, Changsha, Hunan, China.
Chunbing ZhengR&D Department, Changsha Institute of Industrial Technology for Stem Cell and Regenerative Medicine, Changsha, Hunan, China.
Haisong LiuSchool of Biomedical Sciences, Hunan University, Changsha, Hunan, China.ORCID 0000-0002-7645-0855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conventional therapies for endocrine hormone deficiencies, including hormone replacement therapy and solid organ transplantation, are hampered by the lack of physiological regulation or donor shortage, respectively. Directed differentiation of human pluripotent stem cells has opened new avenues for cell replacement therapy; however, research on different endocrine glands has long been conducted in isolation, with limited cross-disciplinary exchange of technical expertise. This Review takes the clinically most advanced stem cell-derived pancreatic β cells as a methodological reference and establishes a three-tier translational challenge model-cell identity,

Indexed as

Cell- and Tissue-Based TherapyEndocrine System DiseasesStem CellsStem Cell TransplantationAnimalsCell DifferentiationHumansInsulin-Secreting Cellsadrenalpancreatic β cellsparathyroidpituitarystem cellthyroid

Identifiers

PMID42685680
PMCPMC13539009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.