Evidence map›Paper›PMID 42685195›Full record

ArticleScience advances2026

Digital twins are funhouse mirrors: Five systematic distortions.

Tianyi Peng, Melanie Brucks, George Gui, Daniel J Merlau, Grace Jiarui Fan, Malek Ben Sliman, Eric J Johnson, Abdullah Althenayyan, Silvia Bellezza, Dante Donati and 13 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Tianyi PengColumbia University, New York, NY 10027, USA.ORCID 0000-0002-9046-3206
Melanie BrucksColumbia University, New York, NY 10027, USA.ORCID 0000-0003-0284-2837
George GuiColumbia University, New York, NY 10027, USA.
Daniel J MerlauColumbia University, New York, NY 10027, USA.ORCID 0009-0005-7760-2987
Grace Jiarui FanColumbia University, New York, NY 10027, USA.
Malek Ben SlimanColumbia University, New York, NY 10027, USA.ORCID 0000-0002-0294-4828
Eric J JohnsonColumbia University, New York, NY 10027, USA.ORCID 0000-0001-7797-8347
Abdullah AlthenayyanColumbia University, New York, NY 10027, USA.ORCID 0009-0001-5919-3324
Silvia BellezzaColumbia University, New York, NY 10027, USA.ORCID 0009-0004-2120-0922
Dante DonatiColumbia University, New York, NY 10027, USA.ORCID 0000-0001-9661-7299
Hortense FongColumbia University, New York, NY 10027, USA.ORCID 0000-0003-0256-7943
Elizabeth FriedmanColumbia University, New York, NY 10027, USA.ORCID 0000-0003-0930-5049
Ariana GuevaraColumbia University, New York, NY 10027, USA.ORCID 0009-0000-4029-761X
Mohamed HusseinColumbia University, New York, NY 10027, USA.
Kinshuk JerathColumbia University, New York, NY 10027, USA.
Bruce KogutColumbia University, New York, NY 10027, USA.ORCID 0000-0003-1355-9738
Akshit KumarYale University, New Haven, CT 06511, USA.ORCID 0000-0002-3418-2514
Kristen LaneColumbia University, New York, NY 10027, USA.ORCID 0000-0002-7917-8703
Hannah LiColumbia University, New York, NY 10027, USA.
Vicki MorwitzColumbia University, New York, NY 10027, USA.ORCID 0000-0002-7983-9604
Oded NetzerColumbia University, New York, NY 10027, USA.ORCID 0000-0002-0099-8128
Patryk PerkowskiYeshiva University, New York, NY 10033, USA.
Olivier ToubiaColumbia University, New York, NY 10027, USA.ORCID 0000-0001-7493-9641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scientists and practitioners are aggressively moving to deploy digital twins-large language model (LLM)-based models of individuals-across social science and policy research. We conducted 19 preregistered studies with 164 diverse outcomes (e.g., attitudes toward hiring algorithms and intention to share misinformation) and compared human responses with those of their digital twins (trained on each person's previous answers to more than 500 questions). We establish an empirical benchmark for digital twin performance: Digital twins' answers are only modestly more accurate than those from the (homogeneous) base LLM and correlate weakly with human responses (average correlation coefficient of 0.20). To guide future development, we document five ways in which digital twins distort human behavior: (i) insufficient individuation, (ii) stereotyping, (iii) representation bias, (iv) ideological biases, and (v) hyper-rationality. We make our full dataset and code public as a standardized testbed. Our results caution against premature deployment while laying the groundwork for the transparent, replicable, and iterative science necessary for responsible deployment of digital twins.

Indexed as

Large Language ModelsAlgorithmsHumansStereotyping

Identifiers

PMID42685195
PMCPMC13537255

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.