ArticleScience advances2026
Digital twins are funhouse mirrors: Five systematic distortions.
Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Surfacing Suicidal Risk Through Simulated Social Interaction: Per-Person Language Model Agents as Communicative Stress Tests.medRxiv : the preprint server for health sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Scientists and practitioners are aggressively moving to deploy digital twins-large language model (LLM)-based models of individuals-across social science and policy research. We conducted 19 preregistered studies with 164 diverse outcomes (e.g., attitudes toward hiring algorithms and intention to share misinformation) and compared human responses with those of their digital twins (trained on each person's previous answers to more than 500 questions). We establish an empirical benchmark for digital twin performance: Digital twins' answers are only modestly more accurate than those from the (homogeneous) base LLM and correlate weakly with human responses (average correlation coefficient of 0.20). To guide future development, we document five ways in which digital twins distort human behavior: (i) insufficient individuation, (ii) stereotyping, (iii) representation bias, (iv) ideological biases, and (v) hyper-rationality. We make our full dataset and code public as a standardized testbed. Our results caution against premature deployment while laying the groundwork for the transparent, replicable, and iterative science necessary for responsible deployment of digital twins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.