Evidence map›Paper›PMID 42684845›Full record

ArticleMolecular biology of the cell2026

Organelle scaling over a 100-fold cell size range.

Alison C E Wirshing, Daniel J Lew

Abstract read
In one paragraph

Article in Molecular biology of the cell, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alison C E WirshingDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.
Daniel J LewDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.ORCID 0000-0001-7482-3585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell volume in a proliferating cell population generally varies over a limited range (∼two to four-fold). Within such populations, organelle content increases with cell volume, maintaining a relatively constant organelle density (amount per cell volume). However, cells of different types can differ greatly in cell volume as well as in organelle composition. In such cases, it is often unclear to what degree, if any, the differences in organelle composition are due to the difference in cell volume. In principle, this issue could be resolved by examining situations where a proliferating population of cells of the same cell type exhibits much greater volume variation. Here we characterize how organelle content scales with cell volume in the polymorphic fungus,

Indexed as

AscomycotaOrganellesCell SizeEndoplasmic ReticulumMitochondriaOrganelle SizePeroxisomesVacuoles

Identifiers

PMID42684845
PMCPMC13637725

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.