ArticleGeneral thoracic and cardiovascular surgery2026
Pre-emptive combined serratus anterior plane block and early recovery after minimally ınvasive direct coronary artery bypass: a retrospective cohort study.
Article in General thoracic and cardiovascular surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMinimally invasive direct coronary artery bypass (MIDCAB) via left anterior thoracotomy causes substantial early pain requiring opioids. The serratus anterior plane block (SAPB) is opioid-sparing, but data on a pre-emptive combined approach are limited. We evaluated its association with opioid administration and early recovery.
methodsAdults undergoing MIDCAB (January-December 2025) were retrospectively grouped by pre-emptive combined SAPB versus standard systemic analgesia. The primary outcome was 24-h postoperative intravenous morphine administration. Secondary outcomes were total morphine-equivalent administration including rescue tramadol, visual analogue scale pain scores, rescue analgesia, time to extubation, intensive care unit (ICU) and hospital stay, and opioid-related adverse events.
resultsSixty-four patients were analyzed (SAPB, n = 33; control, n = 31). Twenty-four-hour intravenous morphine administration was lower with SAPB (9.15 ± 2.56 vs 12.71 ± 3.71 mg, p < 0.001), as was total morphine-equivalent administration (9.72 ± 3.14 vs 19.11 ± 5.80 mg, p < 0.001). Pain scores were lower at 12 h (1 [0-2] vs 4 [3-5]) and 24 h (0 [0-1] vs 3 [2-4]) (both p < 0.001), rescue analgesia was less frequent (6.1% vs 74.2%, p < 0.001), and extubation was earlier (4 [4, 5] vs 8 [6-10] hours, p < 0.001). ICU stay showed a non-significant trend (p = 0.052) and hospital stay was similar (p = 0.414). Opioid-related adverse events did not differ significantly (9.1% vs 29.0%, p = 0.057).
conclusionsPre-emptive combined SAPB was associated with lower opioid administration, better pain control, and earlier extubation after MIDCAB.
Indexed as
Identifiers
42684576What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.