Evidence map›Paper›PMID 42684514›Full record

ArticleClinical oral investigations2026

Evaluation of the physicochemical properties and adhesive interface quality of BioRoot Flow and BioRoot RCS endodontic sealers: An in vitro study.

Dione Tavares Reis, Gustavo Alexandre de Castro-Vasconcelos, Gustavo Creazzo, Helena Cristina de Assis, Igor Bassi Ferreira Petean, Manoel Damiao de Sousa-Neto, Jardel Francisco Mazzi-Chaves, Fabiane Carneiro Lopes-Olhê

Abstract read
In one paragraph

Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dione Tavares ReisDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0009-0001-0526-0835
Gustavo Alexandre de Castro-VasconcelosDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0009-0005-6758-974X
Gustavo CreazzoDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0009-0001-2911-009X
Helena Cristina de AssisDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0000-0001-7492-0385
Igor Bassi Ferreira PeteanDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0000-0002-2704-5730
Manoel Damiao de Sousa-NetoDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0000-0002-7696-7600
Jardel Francisco Mazzi-ChavesDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil.ORCID https://orcid.org/0000-0002-9889-1790
Fabiane Carneiro Lopes-OlhêDepartment of Restorative Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo (USP), Av. do Café, s/n., Ribeirão Preto, SP, 14020-904, Brazil. fabiane.lopes@usp.br.ORCID https://orcid.org/0000-0003-4375-3371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBioceramic sealers have been increasingly used in endodontics due to their favorable physicochemical and biological properties. However, evidence regarding the physicochemical properties, push-out bond strength, and adhesive interface characteristics of BioRoot Flow compared with other root canal sealers remains limited. Therefore, this study evaluated the physicochemical properties, push-out bond strength, failure pattern, and adhesive interface quality of BioRoot Flow (BRF), BioRoot RCS (BRR), and the epoxy resin-based sealer AH Plus (AHP).

methodsSetting time, dimensional change, solubility, radiopacity, and flow were assessed following ANSI/ADA Specification No. 57. Setting time was recorded using cylindrical molds tested with a Gillmore needle. Dimensional change was measured in five specimens per sealer before and after 30 days in distilled water. Solubility was assessed in ten specimens after seven days of immersion, followed by desiccation. Radiopacity was evaluated using acrylic plates radiographed beside an aluminum step wedge. Flow was assessed according to ANSI/ADA standards. For bond strength and interface analysis, thirty single-rooted teeth were prepared with the Reciproc system and irrigated with sodium hypochlorite and EDTA. Canals were obturated with the single-cone technique using the tested sealers (n = 10). Three slices were obtained from each root third; two were used for push-out testing and failure analysis, and one for confocal laser scanning microscopy.

resultsAHP showed the shortest setting time, highest radiopacity, and greatest flow. BRF exhibited the highest solubility, while dimensional change did not differ among materials. Bond strength varied significantly among sealers and root thirds; AHP presented the highest values, followed by BRF and BRR. Adhesive failures predominated for AHP, whereas bioceramic sealers showed mainly mixed failures.

conclusionAHP demonstrated superior physicochemical properties, higher bond strength, and better adhesive interface adaptation. BRF performed better than BRR regarding bonding and interface quality.

Indexed as

Dental BondingRoot Canal Filling MaterialsEpoxy ResinsHumansIn Vitro TechniquesMaterials TestingSolubilitySurface Propertiesepoxy resin-based root canal sealerEpoxy ResinsRoot Canal Filling MaterialsBioceramic sealerBond strengthPhysicochemical properties

Identifiers

PMID42684514
PMCPMC13538271

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.