Evidence map›Paper›PMID 42684435›Full record

ArticleNeuroradiology2026

Clinical outcome after rescue intracranial stenting: a comparison of the ACCLINO flex and the CREDO heal stenting platforms after failed mechanical thrombectomy.

Christoph M Mooshage, Niclas Schmitt, Fabian Preisner, Tim Hilgenfeld, Kianush Karimian-Jazi, Michael O Breckwoldt, Daniel Schwarz, Alexander Hubert, Sophia Hohenstatt, Julius M Kernbach and 7 more

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Article in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Christoph M MooshageDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Niclas SchmittDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0003-2509-5459
Fabian PreisnerDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0003-0314-6761
Tim HilgenfeldDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-3458-8899
Kianush Karimian-JaziDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Michael O BreckwoldtDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-9980-2390
Daniel SchwarzDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-9017-8245
Alexander HubertDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Sophia HohenstattDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0003-0951-3948
Julius M KernbachDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Alexandra FilipovNeurological Clinic, University Hospital Heidelberg, Heidelberg, Germany.
Damjan MirkovNeurological Clinic, University Hospital Heidelberg, Heidelberg, Germany.
Peter A RinglebNeurological Clinic, University Hospital Heidelberg, Heidelberg, Germany.
Christian HerwehDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-9223-9662
Martin BendszusDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Dominik F VollherbstDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany.
Markus A MöhlenbruchDepartment of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany. markus.moehlenbruch@med.uni-heidelberg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMechanical thrombectomy (MT) is the first-line therapy for patients with acute ischemic stroke due to large vessel occlusion; however, despite substantial advances in MT techniques and devices, mechanical recanalization remains unsuccessful in up to 15% of patients. Intracranial rescue stenting represents a promising option to achieve successful recanalization and good clinical outcomes in patients with failed MT.

methodsIn this retrospective, observational single-center analysis 77 consecutive patients who underwent failed MT and a maximum of 4 unsuccessful device passes were included. The ACCLINO flex stent / CREDO

resultsA clinically favorable outcome was achieved in 64.1% (25/39) of patients treated with the CREDO heal stent and in 39.5% (15/38) of patients treated with the ACCLINO flex stents (p = 0.031). Rescue stenting with the CREDO heal stent (aOR 3.51 95% CI 1.11-11.13, p = 0.033), baseline NIHSS (aOR 0.97 95% CI 0.85-0.97, p = 0.005) and pmRS (aOR 0.52 95% CI 0.31-0.89, p = 0.016) were independently associated with a favorable clinical outcome. Baseline characteristics did not differ between both groups.

conclusionsThis study suggests that the design of the implanted stent device may influence the clinical outcome. Features such as optimized radial force and thrombogenicity-reducing surfaces of stents used for RIS may improve clinical outcomes of patients treated with intracranial rescue stenting in unsuccessful MT. These findings are hypothesis-generating and require confirmation in prospective, randomized studies.

Indexed as

Endovascular proceduresStentsStrokeThrombectomy

Identifiers

PMID42684435

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.