ArticleMagnetic resonance in medicine2026
Venous Oxygenation Measurements in the Upper Arm: Reproducibility and Sensitivity to a Physical Challenge.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
purposeThe feasibility and reproducibility of adapting the T2-Relaxation-Under-Spin-Tagging (TRUST) MRI sequence for noninvasive measurement of venous oxygenation in the upper arm were investigated, aiming to enable future in vivo validation of T
methodsThe TRUST sequence, originally developed for the brain, was optimized for the upper arm by comparing control, label and difference signal. Accuracy was assessed using a phantom experiment. Twelve healthy volunteers underwent repeated TRUST scans using two different protocols: Three-averages and One-average. Reproducibility and temporal resolution were investigated, and a handgrip exercise was used to assess sensitivity to physiological changes. Statistical analyses included coefficient of variation (CV), within-subject CV (wsCV), and Bland-Altman analysis.
resultsPhantom experiments demonstrated accurate T
conclusionThe adapted TRUST protocol enables reproducible assessment of venous oxygenation in the upper arm, providing a technique for future validation and recalibration of T
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